Results 91 to 100 of about 502,626 (343)

Impact of managed clinical networks on neonatal care in England : a population-based study [PDF]

, 2012
Objective: To assess the impact of reorganisation of neonatal specialist care services in England after a UK Department of Health report in 2003. Design: A population-wide observational comparison of outcomes over two epochs, before and after the ...
Gale, C., Modi, N., Nagarajan, S., Santhakumaran, S., Statnikov, Y.   +4 more
core  

EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways

Advanced Science, EarlyView.
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen, Ying Li, Yan Yu, Mingze Cai, Hao Li, Minghe Huang, Guochao Yang, Jiageng Guo, Huailin Wang, Zhihong Song, Wei Shen, Huihui Jiang, Haitao Wu   +12 more
wiley   +1 more source

Providing immediate neonatal care and resuscitation at birth beside the mother: clinicians' views, a qualitative study [PDF]

, 2015
Objectives: The aims of this study were to assess clinicians’ views and experiences of providing immediate neonatal care at birth beside the mother, and of using a mobile trolley designed to facilitate this bedside care.
Arnold, Boie, Braun, Critchell, Doyle, Dudley, Duley, Halm, Harteveldt, Harvey, Hutchon, Jabre, Lee, Moons, O'Connell, Pushpa-Rajah, Resuscitation Council, Robinson, Sawyer, Schoonakker, Thomas   +20 more
core   +2 more sources

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

Advanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang, Kaifan Niu, Wei Liu, Xinyun Wang, Boshen Yang, Taixi Li, Yizhi Chen, Yuanyuan Jin, Yu Chen, Yangyi Lin, Xian Jin   +10 more
wiley   +1 more source

Stressors of Parents of Hospitalized Preterm Infants: a study in Neonatal Intensive Care Unit of Afzalipour Hospital, Kerman, Iran [PDF]

, 2015
Background: Birth is a pleasant event, but premature birth and subsequently neonate hospitalization in the neonatal intensive care unit, is stressful for parents.
Baniasadi, Hamideh, Hosseini, Sakineh Sadat, Pouraboli, Batool   +2 more
core  

Limited Depressive and Anxiety Symptoms Late in Pregnancy Are Not Related to Neonatal Outcomes [PDF]

, 2015
Background: Prior studies have reported inconsistent findings regarding the link between antenatal depressive and anxiety symptomatology, with neonatal outcomes.
Kalogerakis, Z., Moraitou, M., Spyropoulou, A. C., Varela, P., Zervas, I. M.   +4 more
core   +1 more source

Next-generation sequencing for diagnosis of rare diseases in the neonatal intensive care unit

Canadian Medical Association Journal, 2016
Background: Rare diseases often present in the first days and weeks of life and may require complex management in the setting of a neonatal intensive care unit (NICU).
H. Daoud, S. Luco, Rui Li, E. Bareke, C. Beaulieu, O. Jarinova, N. Carson, S. Nikkel, G. Graham, J. Richer, C. Armour, D. Bulman, P. Chakraborty, M. Geraghty, Matthew A Lines, T. Lacaze‐Masmonteil, J. Majewski, K. Boycott, D. Dyment   +18 more
semanticscholar   +1 more source

Single‐Cell Transcriptome Profiling Reveals Conserved IFNγ‐IL8 Signaling‐Induced Antibacterial Neutrophil States during Bacterial Infection

Advanced Science, EarlyView.
SummaryThis study constructs a single‐cell immune atlas of Nile tilapia across multiple time points during Streptococcus agalactiae infection, revealing dynamic immune cell responses and subtype transitions. It identifies a conserved IFNr‐STAT1‐IL8 axis driving il8+ neutrophils activation and antibacterial function, supported by cross‐species ...
Xue Zhai, Minghao Zhang, Kang Li, Wei Li, Xiaolong Li, Wa Gao, Zhaosheng Sun, Dan Huang, Songqian Huang, Mingli Liu, Zhichao Wu, Jun Zou, Liangbiao Chen, Jialong Yang, Peng Hu   +14 more
wiley   +1 more source

Repercussion of noise in the neonatal intensive care unit [PDF]

, 2013
OBJECTIVE: To identify repercussion of noise in the neonatal intensive care unit on mothers, newborns and on interactions of neonates with healthcare professional from the mothers' perspective.
Balieiro, Maria Magda Ferreira Gomes, Grecco, Gabriela Menossi, Kakehashi, Tereza Yoshiko, Pinheiro, Eliana Moreira, Tsunemi, Miriam Harumi   +4 more
core   +2 more sources

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Advanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez, Maria Virginia Giolito, Sultan Al‐Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa, Christiani Andrade Amorim, Barabara Pachikian, Yvan Larondelle, Cyril Corbet, Chantal Dessy, Olivier Feron   +20 more
wiley   +1 more source