Results 31 to 40 of about 100,253 (268)

Therapeutic Hypothermia in Asphyxiated Neonates: Experience from Neonatal Intensive Care Unit of University Hospital of Marrakech

International Journal of Pediatrics, 2017
Introduction. Therapeutic hypothermia (TH) is now recommended for the treatment neonates with hypoxic-ischemic encephalopathy (HIE). This treatment protocol is applied in our department since June 2012.
F. M. R. Maoulainine, M. Elbaz, S. Elfaiq, G. Boufrioua, F. Z. Elalouani, M. Barkane, Nadia El Idrissi Slitine   +6 more
doaj   +1 more source

Antimicrobial Resistance Pattern and Empirical Antibiotic Treatments in Neonatal Sepsis: A Retrospective, Single-Center, 12-Year Study

Antibiotics, 2023
Neonatal sepsis is an important cause of morbidity and mortality in neonatal intensive care units (NICUs). Continuous evaluation of antimicrobial resistance (AMR) profiles is advised to implement antimicrobial stewardship (AMS) programs and establish ...
Chiara Minotti, Antonella Di Caprio, Laura Facchini, Luca Bedetti, Francesca Miselli, Cecilia Rossi, Elisa Della Casa Muttini, Licia Lugli, Laura Luppi, Filippo Ferrari, Alberto Berardi   +10 more
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Managing Drug-Resistant Epilepsy and Severe Feeding Difficulties in Miller–Dieker Syndrome: The Role of Enteral Ketogenic Diet

Case Reports in Pediatrics
Miller–Dieker syndrome (MDS) is a rare genetic disorder characterized by classical lissencephaly, severe neurodevelopmental impairment, and early-onset drug-resistant epilepsy.
Perrone Michela, Porro Matteo, Piemontese Pasqua, Roggero Paola, Gangi Silvana, Fumagalli Monica   +5 more
doaj   +1 more source

Update on COVID-19 in the pediatric population at University Hospital of Oran. A retrospective study [PDF]

Batna Journal of Medical Sciences
Introduction. The spread of the novel coronavirus SARS-CoV-2, discovered in China in January 2020, led to a pandemic in Algeria as early as February. Children and adolescents under the age of 18 were much more rarely affected than adults and account ...
Djamila-Djahida BATOUCHE, Zakaria Zoheir ADDOU, Kamel ELHALIMI, Amel BOUGUERRA, Fouzia BOUNOUA, Djilali BATOUCHE, Sid Ahmed BAKRI, Houcine SADDOK, Fatima Zohra LATRECHE, Sara-Halima MOHAMMEDI   +9 more
doaj   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Comparison of three clinical scoring tools for bronchiolitis to predict the need for respiratory support and length of stay in neonates and infants up to three months of age

Frontiers in Pediatrics, 2023
BackgroundBronchiolitis severity can be assessed using different clinical scores. Some of the most used are the Wang Bronchiolitis Severity Score (WBSS), the Kristjansson Respiratory Score (KRS), and the Global Respiratory Severity Score (GRSS ...
Domenico Umberto De Rose, Chiara Maddaloni, Ludovica Martini, Annabella Braguglia, Andrea Dotta, Cinzia Auriti   +5 more
doaj   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

Advanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni, Costantino Casale, Marika Sperduti, Nevio L. Tagliamonte, Giorgia Imparato, Loredana Zollo, Paolo A. Netti   +6 more
wiley   +1 more source

Circular RNA cZNF292 silence alleviates OGD/R-induced injury through up-regulation of miR-22 in rat neural stem cells (NSCs)

Artificial Cells, Nanomedicine, and Biotechnology, 2020
Background Hypoxic-ischaemic encephalopathy (HIE) is a prevailing severe brain damage disease in newborns, and caused by perinatal asphyxia cerebral ischaemia and reperfusion.
Yaqin Cao, Hui Liu, Jun Zhang, Yubin Dong   +3 more
doaj   +1 more source