Results 81 to 90 of about 2,843,398 (403)

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Neonatal mortality risk assessment using SNAPPE- II score in a neonatal intensive care unit

BMC Pediatrics, 2019
BackgroundThere are many scoring systems to predict neonatal mortality and morbidity in neonatal intensive care units (NICU). One of the scoring systems is SNAPPE-II (Score for Neonatal Acute Physiology with Perinatal extension-II).
Dipak Muktan, R. Singh, N. Bhatta, D. Shah   +3 more
semanticscholar   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Trends of Neonatal Mortality in context of Case Overload in Al - Alwyia Pediatric Teaching Hospital at Baghdad during 2005-2012

مجله كليه طب الكندي, 2016
Background: Data on the impact of neonatal and total pediatric admissions volume on neonatal mortality are sparse. Objectives: This study is done to estimate the neonatal mortality in relation to neonatal admissions and to total hospital admissions in ...
Tareef Fadhil Raham, Assad Muhsen Abood
doaj   +1 more source

Gender variations in neonatal and early infant mortality in India and Pakistan: a secondary analysis from the Global Network Maternal Newborn Health Registry

Reproductive Health, 2020
Background To determine the gender differences in neonatal mortality, stillbirths, and perinatal mortality in south Asia using the Global Network data from the Maternal Newborn Health Registry.
Zubair H. Aghai, Shivaprasad S. Goudar, Archana Patel, Sarah Saleem, Sangappa M. Dhaded, Avinash Kavi, Parth Lalakia, Farnaz Naqvi, Patricia L. Hibberd, Elizabeth M. McClure, Tracy L. Nolen, Pooja Iyer, Robert L. Goldenberg, Richard J. Derman   +13 more
doaj   +1 more source

Gestational age patterns of fetal and neonatal mortality in Europe: results from the Euro-Peristat project. [PDF]

PLoS ONE, 2011
BACKGROUND: The first European Perinatal Health Report showed wide variability between European countries in fetal (2.6-9.1‰) and neonatal (1.6-5.7‰) mortality rates in 2004.
Ashna D Mohangoo, Simone E Buitendijk, Katarzyna Szamotulska, Jim Chalmers, Lorentz M Irgens, Francisco Bolumar, Jan G Nijhuis, Jennifer Zeitlin, Euro-Peristat Scientific Committee   +8 more
doaj   +1 more source

The effect of HIV status on perinatal outcome at Mowbray Maternity Hospital and referring MOUs [PDF]

, 2011
Includes bibliographical referencesBackground: 33,4 Million people were living with the Human Immune Deficiency virus by the end of 2009 with sub-Saharan Africa the most affected region.
Kennedy, Deon
core  

Advances in prevention and therapy of neonatal dairy calf diarrhoea : a systematical review with emphasis on colostrum management and fluid therapy [PDF]

, 2014
Neonatal calf diarrhoea remains the most common cause of morbidity and mortality in preweaned dairy calves worldwide. This complex disease can be triggered by both infectious and non-infectious causes.
A Coskun, A Koch, A Rodriguez-Palacios, A Stieler, AA Sadeghi, ACB Berge, ACB Berge, ACB Berge, ACB Berge, AJ Reber, AJ Reber, AJ Reber, AL Beam, AP Fidler, B Elitok, BD Jarvie, C Maddox-Hyttel, C Silverlås, C Silverlås, C Svensson, CG Todd, CJM Bartels, CM Jones, D Priestley, DC Donovan, DE Morin, DM Foster, FL Uhde, FM Trefz, FM Trefz, FM Trefz, FM Trefz, Geert Hoflack, Geert Opsomer, GW Smith, H Swan, I Lorenz, I Lorenz, I Lorenz, I Lorenz, I Sen, JA Elizondo-Salazar, JA Elizondo-Salazar, JB Ewaschuk, JB Ewaschuk, JD Quigley, JF Berchtold, JL Johnson, K Furman-Fratczak, K Poulsen, K Urday, KM Morrill, KN Galvão, L Bachmann, LA Trotz-Williams, LA Trotz-Williams, LA Trotz-Williams, LA Trotz-Williams, LA Trotz-Williams, LH Wieler, M Chigerwe, M Chigerwe, M Chigerwe, M Chigerwe, M Donahue, M Kaske, M Kváč, M Lallemond, M Medina-Cruz, M Moore, M Nouri, M Ok, M Sahal, M Santin, M Santín, M Schnyder, MC Windeyer, MM Izzo, N Chand, P Klein, PD Constable, PD Constable, PD Constable, PS Morley, R Kirisawa, R Russell Sakai, R Von Buenau, RR Rastani, S Godden, S McMartin, S Reinhold, S Stewart, SI Kehoe, SL Gelsinger, SM Godden, SM Godden, SM Godden, SM Gulliksen, SM Gulliksen, SS Aly, T Geurden, TS Marshall, UT Bleul, V Bielmann, V De Waele, VA Bampidis, Vanessa Meganck, Ö Güngör   +107 more
core   +2 more sources

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Birth order, gestational age, and risk of delivery related perinatal death in twins: retrospective cohort study [PDF]

, 2002
Objective: To determine whether twins born second are at increased risk of perinatal death because of complications during labour and delivery. Design: Retrospective cohort study. Setting: Scotland, 1992 and 1997.
Dobbie, R., Pell, J.P., Smith, G.C.
core   +3 more sources