Results 121 to 130 of about 442,503 (290)

The role of electroencephalogram in neonatal seizure detection

, 2017
The role of EEG in neonatal seizure detection is well-established, being the multichannel video-EEG the gold standard. However, in the clinical practice often amplitude integrated EEG (aEEG) is used, in order to overcome the difficulties related to EEG ...
Pavlidis, Elena, Pisani, Francesco, Francesco Pisani, Pavlidis E., Pisani F., Elena Pavlidis   +5 more
core   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

A Novel Reactive Oxygen Species‐Responsive Bone‐Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy‐Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

Advanced Science, EarlyView.
Cloperastine suppresses osteoclastogenesis by inhibiting PGC1β‐mediated oxidative phosphorylation. Its incorporation into a ROS‐responsive, Asp8‐modified nanoplatform enhances skeletal accumulation. The resulting Clo/Asp8‐PMK‐MCs combine cloperastine‐mediated antiresorptive activity with carrier‐mediated osteogenic activity to attenuate OVX‐induced ...
Haibo Liang, Yong Xiao, Jiangtao Luo, Xiao Yang, Yayun Yang, Qihang Wu, Chenxin Yu, Zhihao Zhou, Xiaoqing Si, Jiansen Miao, Yiting Tu, Qichen Lu, Boreng Qian, Xiangyang Wang, Jiake Xu, Changcan Shi, Haiming Jin   +16 more
wiley   +1 more source

Acute seizure activity in neonatal inflammation-sensitized hypoxia-ischemia in mice.

PLoS ONE
ObjectiveTo examine acute seizure activity and neuronal damage in a neonatal mouse model of inflammation-sensitized hypoxic-ischemic (IS-HI) brain injury utilizing continuous electroencephalography (cEEG) and neurohistology.MethodsNeonatal mice were ...
Angelina June, Weronika Matysik, Maria Marlicz, Emily Zucker, Pravin K Wagley, Chia-Yi Kuan, Jennifer Burnsed   +6 more
doaj   +1 more source

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source

Prominent astrocytic GLAST pathology occurs in newborn human and piglet hypoxic–ischemic encephalopathy: modeling relationships among laminar neuropathology, seizures, and therapeutic hypothermia

Frontiers in Cellular Neuroscience
Neonatal hypoxic–ischemic encephalopathy (HIE) is frequently complicated by seizures that persist despite therapeutic hypothermia (HT), suggesting injury mechanisms insensitive to HT.
Dongseok Park, Caitlin E. O’Brien, Jennifer K. Lee, Lee J. Martin, Lee J. Martin, Lee J. Martin, Lee J. Martin   +6 more
doaj   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Probe into Carrying out Health Education for Parents in the Observation of Neonatal Seizures

Huli yanjiu, 2003
Objective: in order find out neonatal seizures in time, to decrease their seizures induced brain damage. Methods: a total of 196 newborns with high risk of seizures attack were divided into both test and control groups randomly. Parent of test group were
霍世英
doaj  

Leveraging electronic medical record-embedded standardised electroencephalogram reporting to develop neonatal seizure prediction models: a retrospective cohort study. [PDF]

Lancet Digit Health, 2023
McKee JL, Kaufman MC, Gonzalez AK, Fitzgerald MP, Massey SL, Fung F, Kessler SK, Witzman S, Abend NS, Helbig I.   +9 more
europepmc   +1 more source

Eames Overload and the Mystification Machine: The IBM Pavilion at the 1964 New York World's Fair

, 2011
Critical essay on Charles & Ray Eames' work for IBM at the 1964 New York World's Fair.
Stein, JA
core