Results 31 to 40 of about 442,503 (290)

Modelling hyperexcitability in human cerebral cortical organoids: Oxygen/glucose deprivation most effective stimulant

open access: yesHeliyon, 2023
Epilepsy is a common neurological disorder that affects 1% of the global population. The neonatal period constitutes the highest incidence of seizures.
Afifa Saleem   +5 more
doaj   +1 more source

Case Report: Effect of Targeted Therapy With Carbamazepine in KCNQ2 Neonatal Epilepsy

open access: yesFrontiers in Neurology, 2022
We present a family case of neonatal-onset KCNQ2-related epilepsy due to a novel intronic mutation. Three members of an Italian family (father and offspring) presented with neonatal-onset asymmetric tonic and clonic seizures with peculiar video ...
Robertino Dilena   +10 more
doaj   +1 more source

Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels

open access: yesMolecular Brain, 2019
Neonatal seizures are different from adult seizures, and many antiepileptic drugs that are effective in adults often fail to treat neonates. Here, we report that gluconate inhibits neonatal seizure by inhibiting CLC-3 chloride channels.
Zheng Wu   +13 more
doaj   +1 more source

Treatment of neonatal seizures [PDF]

open access: yesArchives of Disease in Childhood - Fetal and Neonatal Edition, 2007
Newborn babies with unusual movements thought to represent seizures are usually given a loading dose of phenobarbitone without electroencephalography being performed. Antiepileptic drugs (AEDs) are then continued, with the outcome determined by clinical observation alone. AED treatment, often involving multiple drugs for long periods, is undesirable at
Janet, Rennie, Geraldine, Boylan
openaire   +2 more sources

Designing a trial for neonatal seizure treatment [PDF]

open access: yes, 2018
Neonatal seizures are widely considered a neurological emergency with a need for prompt treatment, yet they are known to present a highly elusive target for bedside clinicians. Recent studies have suggested that the design of a neonatal seizure treatment
Stevenson, Nathan J.   +3 more
core   +1 more source

Protecting the Future: Neonatal Seizure Detection with Spatial-Temporal Modeling [PDF]

open access: yes, 2023
A timely detection of seizures for newborn infants with electroencephalogram (EEG) has been a common yet life-saving practice in the Neonatal Intensive Care Unit (NICU).
Li, Dongsheng   +9 more
core   +1 more source

Neonatal seizure detection algorithms: The effect of channel count

open access: yesCurrent Directions in Biomedical Engineering, 2022
The number of electrodes used to acquire neonatal EEG signals varies between institutions. Therefore, tools for automatic EEG analysis, such as neonatal seizure detection algorithms, need to be able to handle different electrode montages in order to find
Borovac Ana   +3 more
doaj   +1 more source

Development of severe IVH, mortality, and neonatal seizure.

open access: yes, 2019
Development of severe IVH, mortality, and neonatal seizure.
Hyun-Seung Lee (627362)   +1 more
core   +1 more source

Investigating the Impact of CNN Depth on Neonatal Seizure Detection Performance [PDF]

open access: yes, 2018
This study presents a novel, deep, fully convolutional architecture which is optimized for the task of EEG-based neonatal seizure detection. Architectures of different depths were designed and tested; varying network depth impacts convolutional receptive
Temko, Andriy   +7 more
core   +1 more source

Diagnostic Accuracy of the Persyst Automated Seizure Detector in the Neonatal Population

open access: yesJournal of Integrative Neuroscience
Background: Neonatal seizures are diagnostically challenging and predominantly electrographic-only. Multichannel video continuous electroencephalography (cEEG) is the gold standard investigation, however, out-of-hours access to neurophysiology support ...
Eleanor Duckworth   +5 more
doaj   +1 more source

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