Results 31 to 40 of about 1,812,268 (301)

Risk factors for anastomotic complications following thoracoscopic repair of type III esophageal atresia in neonates: a single-center retrospective cohort study

Frontiers in Pediatrics
BackgroundAlthough thoracoscopic repair in China has emerged as a preferred and increasingly adopted minimally invasive approach for esophageal atresia (EA), anastomotic complications remain a major concern, with reported incidences ranging from 15% to ...
Ziwei Zhang, Ziwei Zhang, Like Yuan, Meng Li, Xiaochun Zhu, Wuping Ge, Jialiang Zhou, Lu Xu, Song Tian, Yuanlong Fang, Rong Huang, Xinyue Li, Xinyue Li, Yasi Wang, Yasi Wang, Shangjie Xiao, Shangjie Xiao   +16 more
doaj   +1 more source

Assessment of Predictors of Mortality in Neonatal Intestinal Obstruction

, 2018
Background: Neonatal intestinal obstruction (NIO) continues to be a life-threatening condition with high mortality rates especially in developing countries. Highly skilled specialized care and facilities are required for survival.
Sajad Wani, Mudasir Buchh, Imran Ali, Raashid Hamid, Khurshid A Sheikh, Shahid Banday, Nisar A Bhat, Gowhar N Mufti, Zubair Khurshid, Aejaz A Baba, Faheem Andrabi   +10 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Feasibility and impact of three-dimensional (3D) printing technology in simulated teaching of congenital malformations

BMC Medical Education
Aims This study aimed to investigate the feasibility and effectiveness of utilizing three-dimensional (3D) printing technology in the simulation teaching of congenital malformations.
Qi Gao, Qi Wang, Mingming Li, Chaoxiang lu   +3 more
doaj   +1 more source

Neonatal Solitary Intestinal Myofibromatosis

, 2018
Solitary intestinal myofibromatosis (SIF) is a very rare condition affecting the pediatric population and carries good prognosis following adequate management based on segmental resection.
Rachida Laamiri, Nahla Kechiche, Mongi Mekki, Lassaad Sahnoun, Rim Hadhri, Abdellatif Nouri, Meriem Braiki, Mohsen Belghith   +7 more
core   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Early outcomes of tapering jejunoplasty by antimesenteric seromuscular stripping and mucosal inversion for proximal jejunal atresia

Egyptian Pediatric Association Gazette, 2019
Background High jejunal atresia is associated with significant dilatation of the proximal segment. This poses two problems: (a) calibre discrepancy with the distal unused segment and (b) hypomotility causing stasis.
Mahmoud Marei Marei, Mohamed Hamed Abouelfadl, Ahmed Arafa Elsayed Rawwash, Hamed Mahmoud Seleim, Wesam Mohamed Mahmoud, Tamer Yassin Mohamed Yassin, Gamal Hassan El-Tagy   +6 more
doaj   +1 more source

Indocyanine green fluorescence imaging localization-assisted thoracoscopy revision surgery after repair of esophageal atresia

BMC Gastroenterology, 2022
Revision surgery for the complications after repair of esophageal atresia is often complex because of previous surgeries and chest infections and thus requires surgical expertise.
Yanan Zhang, Murong Wang, Shuangshuang Li, Junmin Liao, Kaiyun Hua, Shen Yang, Jinshi Huang   +6 more
doaj   +1 more source

Real‐Time Holographic Feedback via Mixed Reality Sensorized Laryngoscope Training System Enhances Pediatric Intubation Training

Advanced Robotics Research, EarlyView.
We proposed a Mixed Reality Sensorized Laryngoscope Training System to provide real‐time holographic torque feedback during pediatric endotracheal intubation simulation. Visualization formats are evaluated to reduce tracking error and visual demand.
Jiaqi Li, Ryman Hashem, Ningzhe Hou, Perla Maiolino, Louis Halamek, Liang He   +5 more
wiley   +1 more source