Results 51 to 60 of about 1,812,268 (301)

Esophageal atresia with concomitant hypertrophic pyloric stenosis: a case series and literature review

BMC Pediatrics
Background Esophageal atresia (EA) with concomitant hypertrophic pyloric stenosis (HPS) is a rare condition, and its diagnosis can be challenging due to overlapping postoperative complications.
Zhaozhou Liu, An Wang, Dingding Wang, Yong Zhao, Yanan Zhang, Shuangshuang Li, Junmin Liao, Kaiyun Hua, Yichao Gu, Dayan Sun, Jinshi Huang   +10 more
doaj   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Laparoscopic management of congenital gastric muscular layer defect and gastric perforation: a case series

World Journal of Pediatric Surgery
This study aimed to evaluate the feasibility and efficacy of laparoscopic management in neonates diagnosed with congenital gastric muscular layer defects and gastric perforation.
Ying Wu, Xin Guo, Yuanyuan Jin, Hongxia Ren, Xiaoxia Wu, Baohong Zhao, Wenyue Liu   +6 more
doaj   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

Advanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan, Chaowen Bai, Yifei Zhu, Chenyang Xu, Sonngtao Li, Qize Sun, Chang She, Jinyu Bai, Cong Cao, Yitian Yang, Xiaozhong Zhou   +10 more
wiley   +1 more source

A comprehensive diagnostic model based on serum MMP-7: a convenient and efficient early diagnostic method for biliary atresia

BMC Pediatrics
Objective To evaluate the diagnostic value of serum matrix metalloproteinase‑7 (MMP‑7) in biliary atresia (BA) and to develop a predictive model for its early diagnosis.
An Wang, Zhaozhou Liu, Yong Zhao, Yanan Zhang, Shuangshuang Li, Junmin Liao, Kaiyun Hua, Yichao Gu, Chuanping Xie, Yuyan Jin, Dayan Sun, Dingding Wang, Jinshi Huang   +12 more
doaj   +1 more source

Monitoring Cerebral and Renal Oxygenation Status during Neonatal Digestive Surgeries Using Near Infrared Spectroscopy

Frontiers in Pediatrics, 2017
BackgroundDepending on the initial pathology, hypovolemia, intra-abdominal hypertension, and sepsis are often encountered in neonatal digestive surgery.
Jonathan Beck, Gauthier Loron, Claire Masson, Marie-Laurence Poli-Merol, Marie-Laurence Poli-Merol, Eliane Guyot, Camille Guillot, Nathalie Bednarek, Nathalie Bednarek, Caroline François, Caroline François   +10 more
doaj   +1 more source

Effect of case management on neonatal mortality due to sepsis and pneumonia. [PDF]

, 2011
BACKGROUND: Each year almost one million newborns die from infections, mostly in low-income countries. Timely case management would save many lives but the relative mortality effect of varying strategies is unknown.
Bhutta Zulfiqar A, Zulfiqar A Bhutta, Zaidi, Anita K. M., Ganatra, Hammad A, Ganatra Hammad A, Lawn, Joy E, Lawn, Joy E., Lawn Joy E, Joy E Lawn, Cousens Simon, Syed, Sana, Robert Black, Simon Cousens, Zaidi Anita K M, Lee, Anne CC, Black, Robert, Lee Anne CC, Ganatra, Hammad A., Cousens, Simon, Sana Syed, Zaidi, Anita KM, Bhutta, Zulfiqar A, Hammad A Ganatra, Black Robert, Anita K M Zaidi, Bhutta, Zulfiqar A., Anne CC Lee, Lee, Anne C. C., Syed Sana   +28 more
core   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

National Neonatal Transport Programme: clinical report 2004-2008

, 2009
As is internationally recognised, the success of the centralisation of resources and expertise In the area of neonatology Is dependent on a reliable and effective transport service, The NNTP Is achieving this by the provision of: A comprehensive ...
Bowden, Ann
core  

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source