Results 41 to 50 of about 115,482 (301)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Pharmacokinetics of antivirals in neonate
, 2005 Backgrounds: About 1000 neonates with HIV infection are born every day worldwide. The antiviral therapy for newborn infants is a real necessity.
PACIFICI, GIAN MARIA
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Frontiers in PediatricsUlcerative colitis (UC) is a chronic inflammatory bowel disease characterized by severe intestinal barrier dysfunction and immune dysregulation in patients, with limited clinical treatment options. Recent research highlights the important role of the gut
Nie Xu +7 more
doaj +1 more source
A Case of Misdiagnosed Cesarean Scar Pregnancy with a Viable Birth at 28 Weeks
Case Reports in Obstetrics and Gynecology, 2014 We report our experience with a case of presumptive cesarean scar pregnancy, based on detection of a gestational sac (GS) in early pregnancy at the site of a previous cesarean scar. The GS grew into the uterine cavity as the pregnancy progressed, showing
Sakiko Nukaga +4 more
doaj +1 more source
Neurobehavior of term neonates with neonatal hyperbilirubinemia
Journal of Pediatric Neurosciences, 2013 To find the effect of neonatal hyperbilirubinemia on neurobehavior of term infants.This study was undertaken in the neonatal unit of our tertiary care hospital. Term neonates who developed jaundice with serum bilirubin value of above 15 mg/dl within 1(st) week of life were enrolled in the study.
Babu, Thirunavukkarasu Arun +2 more
openaire +3 more sources
Hypothermia in the early neonatal period [PDF]
, 2003 Background: Hypothermia in neonates is a common problem and is associated with increased morbidity and mortality. Prevention of hypothermia is therefore an essential aspect of neonatal care especially in the immediate neonatal period.
Mizzi, Joseph, Sultana, Paul
core
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source