Results 51 to 60 of about 115,482 (301)

Circumvallate Placenta: Associated Clinical Manifestations and Complications—A Retrospective Study

Obstetrics and Gynecology International, 2014
Aims. To analyze the pregnancy outcomes of circumvallate placenta retrospectively and to predict circumvallate placenta during pregnancy based on its clinical features. Methods. The pregnancy outcomes of 92 women with circumvallate placenta who delivered
Hanako Taniguchi, Shigeru Aoki, Kentaro Sakamaki, Kentaro Kurasawa, Mika Okuda, Tsuneo Takahashi, Fumiki Hirahara   +6 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Intrauterine transfusion under fetal analgesia: the evaluation of perinatal outcomes

Frontiers in Pain Research
IntroductionIntrauterine transfusion is the treatment for fetal anemia resulting from maternal alloimmunization, infections (parvovirus B19 and cytomegalovirus), single demise of a monochorionic twin, chorioangioma, and other rare conditions.
Mariano Lanna, Mariano Lanna, Daniela Casati, Daniela Casati, Chiara Bianchi, Chiara Bianchi, Stefano Faiola, Stefano Faiola, Arianna Laoreti, Arianna Laoreti, Francesco Cavigioli, Francesco Cavigioli, Valeria Savasi, Gianluca Lista, Gianluca Lista   +14 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Rare case of Morgagni hernia presenting with cyanotic spells in a neonate

, 2020
.1 Morgagni hernia can be a rare cause of intermittent positional cyanosis without apnoea in a neonate. 2. Intermittent compressive effect of herniated abdominal contents on the right heart can cause right to left shunting of blood through a patent ...
Choo, Kelvin, Sher, Mustafa, Saikiran Gopalakaje, Kelvin Choo, Nitin Kapur, Gopalakaje, Saikiran, Kapur, Nitin, Justo, Robert, Mustafa Sher, Robert Justo   +9 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Determinants of Unwanted Pregnancies Among Pregnant Women Attending Primary Health Care Centres in Kirkuk, Iraq: A Cross-Sectional Study

Babcock University Medical Journal
Objective: This study aimed to determine the prevalence of unwanted pregnancies and examine associated socio-demographic and contraceptive-related factors among pregnant women attending primary healthcare centres in Kirkuk, Iraq, between December 2024 ...
Amina Nabil Shakir, Suhailah Mohammed Ali   +1 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Assessment of Nurses’ Knowledge and Competence in Managing Preeclampsia at Maternity Teaching Hospital in Sulaimani city

UHD Journal of Science and Technology
Background: Preeclampsia is one of the most commonly reported complications during pregnancy, affecting approximately 2–15% of all pregnancies. It is characterized by the onset of hypertension after 20 weeks of gestation, accompanied by proteinuria ...
Amani Fadhil Abbas, Peshwaz Abdulrahman Ahmed, Nazera Salam Mena Qadir, Khanda Gharib Aziz   +3 more
doaj   +1 more source