Results 71 to 80 of about 115,482 (301)

Congenital toxoplasmosis: potential outcomes and therapeutic challenges - a complex case report of the newborn with treatment-resistant manifestations

Journal of Education, Health and Sport
Introduction and purpose Toxoplasmosis, a prevalent parasitic infection caused by Toxoplasma gondii, impacts approximately one-third of the global population.
Emilia Kowalczyk, Sylwia Koziej, Martyna Niemczuk, Adrianna Jasiuk, Mateusz Wiekiera   +4 more
doaj   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar, Laura Marti‐Sánchez, Loreto Martorell, Giorgia Dinoi, Antonio Vittorio Buono, Annamaria De Luca, Antonella Liantonio, Paola Imbrici   +7 more
wiley   +1 more source

Regional Anaesthesia for the Neonate

, 2017
Numerous regional and local anaesthesia techniques are available for safe use in neonates and can be administered either in combination with general anesthesia or in the awake neonate.
Kirti N Saxena, Bharti Wadhwa, Neha Hasija   +2 more
core   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

Arthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J. T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Congenital CMV Infection: A Complex Case of Neurological Complications and Therapeutic Approaches in Infancy

Journal of Education, Health and Sport
Introduction and purpose Congenital Cytomegalovirus (CMV) infection stands as the prevalent infection among newborns and it may be associated with later complications such as progressive sensorineural hearing loss or neurological diseases.
Sylwia Koziej, Emilia Kowalczyk, Martyna Niemczuk, Adrianna Jasiuk, Mateusz Wiekiera   +4 more
doaj   +1 more source

Intensive Care of The Fetus and Neonate

, 2005
xvii.1440 hal.; 28 ...
Spitzer
core  

Immunology of the Bovine Neonate

, 2003
Disease of the bovine neonate can be prevalent and devastating to the producer. The diseases common to neonates are not unique to this age group. However, many are uncommon causes of clinical disease in older animals.
Nagy, Dusty W., Tyler, Jeff W.
core   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Neonatal pain assessment: the development of a pain assessment scale for neonatal transport

, 2014
The aim of this study is to develop a pain assessment scale for use during neonatal transport. Underpinned by the rights of the child to have appropriate assessment and management of pain and the important deleterious effects pain can have on the ...
Raeside, L.
core   +1 more source

NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex

Neurobiology of Disease, 2012
In industrialized countries, cerebral palsy affects 2.5‰ of preterm and term infants. At a neurochemical level, the massive release of glutamate constitutes a major process leading to excitotoxicity and neonatal brain lesions. Previous studies, conducted
Faiza El Ghazi, Arnaud Desfeux, Carole Brasse-Lagnel, Christian Roux, Celine Lesueur, Danielle Mazur, Isabelle Remy-Jouet, Vincent Richard, Sylvie Jégou, Vincent Laudenbach, Stephane Marret, Soumeya Bekri, Vincent Prevot, Bruno J. Gonzalez   +13 more
doaj   +1 more source