Results 171 to 180 of about 242,800 (316)
ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng +19 more
wiley +1 more source
Comparing extracellular vesicle enriched plasma proteomes between term and preterm neonates over the first days of life: post hoc analysis of a prospective observational study. [PDF]
O'Reilly D +11 more
europepmc +1 more source
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar +4 more
wiley +1 more source
Single-port laparoscopic excision of choledochal cysts in neonates versus older infants and children: a comparative safety and feasibility study from a single-center 5-year experience. [PDF]
Yan B +10 more
europepmc +1 more source
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen +14 more
wiley +1 more source
Isolated prenatal foramen ovale closure or restriction presenting after birth: a distinct, under-recognized clinical condition. [PDF]
Podnar T +5 more
europepmc +1 more source
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo +18 more
wiley +1 more source

