Results 191 to 200 of about 266,608 (313)

Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry

Advanced Science, EarlyView.
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally, Kaustav Bera, Nolan R. Petrich, Alex Khang, Marilyne Coulombe, David Castillo‐Azofeifa, Ophir D. Klein, Peter J. Dempsey, Kristi S. Anseth   +8 more
wiley   +1 more source

Incidence of mortality and its predictors among low birth weight neonates in Ethiopia: Systematic review and meta-analysis. [PDF]

PLoS One
Wondie WT, Wubneh CA, Mekonen GB, Legesse BT, Regassa BT, Mamo DN, Gebreegziabher ZA, Abebaw MA, Gedefaw GD, Mengstie LA, Zemariam AB, Zemariam AB.   +11 more
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Machine Learning-Based Prediction of Culture-Confirmed Neonatal Sepsis in a Tertiary Neonatal Intensive Care Unit: Retrospective Cohort Study. [PDF]

JMIR Med Inform
Badran E, Al-Smadi O, Algazo LT, Al Ghazo AT, Al Anber A, Sharaqa A, Abu-Argoub L, Al Jaberi S, Alhanbali A, Yacoub T, Rihan S, Al-Jaberi H.   +11 more
europepmc   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Treatment of Urinary Tract Infections in Neonates and Young Infants: Evidence and Recommendations. [PDF]

Antibiotics (Basel)
Lashkar MO, Nahata MC.
europepmc   +1 more source

The neonatal eye [PDF]

Eye, 1992
openaire   +2 more sources

Prevention of Pain in Neonates

, 2008
Carbajal, Ricardo, Kumar, Praveen, Anand, K.J.S.   +2 more
core   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Clinical epidemiology of easily recognisable congenital malformations in Gambian newborns: a descriptive cohort study embedded in a clinical trial. [PDF]

BMC Pregnancy Childbirth
Graves S, Beloum N, Camara B, Nakakana UN, Danso M, Sillah F, Jones JC, Sabally E, Badjie S, Jarra O, Bah S, Suso A, Ndure E, Njie Y, Bottomley C, Tinto H, D'Alessandro U, Brotherton H, Roca A.   +18 more
europepmc   +1 more source