Results 151 to 160 of about 193,254 (359)

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

DNA methylation signatures of cervical pre‐invasive and invasive disease: An epigenome‐wide association study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Cervical cancer screening programmes could benefit from an accurate triage test for human papillomavirus‐positive women based on self‐sampling. This epigenome‐wide association study examined a large number of cervical cancers and cervical intraepithelial neoplasias grade 3 (CIN3) compared to controls using the 850 k EPIC methylation array ...
Sarah J. Bowden   +9 more
wiley   +1 more source

Screening outcomes at second FIT screening in individuals with a first time negative FIT‐result or low‐risk adenomas: Results from a nationwide FIT screening program

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Fecal immunochemical test (FIT) screening is increasingly common as a population‐based screening tool for colorectal cancer (CRC). If the follow‐up colonoscopy after a positive FIT detects only low‐risk adenomas, those participants are recommended to continue biennial screenings, the same as people with negative FIT results.
Pernille Thordal Larsen   +4 more
wiley   +1 more source

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