Results 31 to 40 of about 86,837 (258)

Sincronismo colorrectal: adenocarcinoma de colon ascendente y carcinoma neuroendocrino de células pequeñas de recto

, 2020
El cancer colorrectal (CCR) es el tercer cancer mas frecuente en el mundo y la segunda causa de muerte de origen neoplasico. El sincronismo en CCR es de aproximadamente 3-6%.
Jhean Gabriel Gonzáles Yovera, Henry Tomas Vargas Marcacuzco, R. Julian, José Luis Arenas Gamio   +3 more
semanticscholar   +1 more source

Comparative study of gene expression by cDNA microarray in human colorectal cancer tissues and normal mucosa [PDF]

, 2006
The causative molecular pathways underlying the pathogenesis of colorectal cancer (CRC) need to be better characterized. The purpose of our study was to better understand the genetic mechanism of oncogenesis for human colorectal cancer and to identify ...
Bianchini, Michele, Carinci, Paolo, De Sanctis, Paola, Levy, Estrella Mariel, Macagno, Carlo, Mordoh, Jose, Pinski, Victor, Valvassori, Luisa, Zucchini, Cinzia   +8 more
core   +1 more source

Proceso diagnóstico para la detección de Cáncer de Colon y Recto

Enfermería Actual de Costa Rica, 2012
Este artículo tiene como objetivo presentar el proceso diagnóstico para la detección de cáncer de colon y recto. El colon, incluyendo el recto, es la víscera donde se origina el mayor número de neoplasias de todo el cuerpo.
Gabriela Marchena Rojas
doaj   +1 more source

The molecular landscape of colitis-associated carcinogenesis [PDF]

, 2016
In spite of the well-established histopathological phenotyping of IBD-associated preneoplastic and neoplastic lesions, their molecular landscape remains to be fully elucidated. Several studies have pinpointed the initiating role of longstanding/relapsing
D'Inca', Renata, Fassan, Matteo, Mescoli, Claudia, Michielan, Andrea, Rugge, Massimo, Saraggi, Deborah, Scarpa, Marco, Valeri, Nicola   +7 more
core   +1 more source

miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene [PDF]

, 2017
Background: Loss of CBX7 expression has been described in several malignant neoplasias, including human colon and thyroid carcinomas proposing CBX7 as a tumor suppressor gene with a key role in cancer progression.
Alfredo Fusco, Claudio Arra, Floriana Forzati, Francesco Esposito, Gianluca Pellino, Marco De Martino, Romina Sepe, Simona Pellecchia, Umberto Malapelle   +8 more
core   +2 more sources

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Neoplasias hepáticas benignas: variantes histológicas, problemas diagnósticos y diagnóstico diferencial

Revista Colombiana de Gastroenterología, 2015
Un principio básico de la patología es que las neoplasias se diferencian según sus células de origen y en el hígado semejan sus constituyentes, sean las células hepáticas, del epitelio biliar, endoteliales, mesenquima- les o una combinación de ...
Rocio del Pilar López Panqueva
doaj   +1 more source

Polyethylene glycol and prevalence of colorectal adenomas : Population-based study of 1165 patients undergoing colonoscopy [PDF]

, 2006
Background and aim — Dietary polyethylene glycol (PEG) is extraordinarily potent in the chemoprevention of experimental colon carcinogenesis. PEG is used to treat constipation in France and in the USA. French laxatives include Forlax® (PEG4000), Movicol®
Barbieux, Jean-Pierre, Bertrand, Philippe, Bougnoux, Philippe, Brondin, Brigitte, Corpet, Denis E., Dorval, Etienne, Jankowski, Jean Marie, Viguier, Jérôme   +7 more
core  

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source