Results 81 to 90 of about 16,350,008 (245)

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Efecto de la administración de queso de búfala sobre el desarrollo del cáncer experimental del colon en ratas

, 2016
Nuestro grupo de investigación ha realizado experiencias con leche de vaca y de búfala, demostrando su efecto inhibidor sobre el desarrollo de cáncer de colon en ratas.
Villordo, Gabriela Inés
core  

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Efeito da suplementação com óleo de peixe sobre o estado nutricional e marcadores inflamatórios em pacientes com neoplasias hematológicas durante a quimioterapia [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2014Neoplasias hematológicas é um grupo heterogêneo de doenças malignas que incluem leucemias e linfomas ...
Chagas, Thayz Rodrigues
core  

Liquid Biopsy and Multi‐Cancer Early Detection Tests for Cancer Screening: A Scoping Review

Clinical Genetics, EarlyView.
There is a large body of evidence on liquid biopsy and multi‐cancer detection tests for cancer screening. Most studies addressed test performance outcomes, while fewer addressed clinical outcomes, implementation, and cost‐effectiveness. No studies evaluated cancer mortality.
Tessa Robinson, Marian Saab, Lily Thao Nguyen, Pooja Kochar, Olivia Meggetto, Jill Tinmouth, Meghan J. Walker   +6 more
wiley   +1 more source

Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]

, 2010
Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Diane Bahuaud, Sylviane Taché, Bahuaud, Diane, Taché, Sylviane, Ossama Allam, Salah Eldin Allam, Ossama, Denis E. Corpet, Pierre, Fabrice, Allam, Ossama, Naud, Nathalie, Pierre, Fabrice H.F., Nathalie Naud, Corpet, Denis E., Fabrice H. F. Pierre   +13 more
core   +1 more source

Metástasis hepáticas en el cáncer colorrectal: estrategias terapéuticas y recomendaciones actuales

Revista Colombiana de Cirugía, 2019
El cáncer colorrectal con metástasis a hígado es una enfermedad frecuente que hasta hace pocos años se consideraba únicamente de tratamiento paliativo.
Diego Dávila, Óscar Palacios, Camilo Naranjo   +2 more
doaj   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Il carcinoma del colon retto metastatico- Sicurezza ed efficiacia di Panitumumab dopo reazioni infusionali da Cetuximab nel carcinoma del colon retto metastatico

, 2012
Raccolta casi clinici sul tumore del colon retto ...
DE LUCA, CRISTINA, LO RUSSO, VALENTINA, GIOVANNONI, SARA, Iolanda Speranza, DI SERI, Marisa   +4 more
core  

Tapeworm testing: Coprological and antibody‐based approaches across colic types in a German equine hospital population

Equine Veterinary Education, EarlyView.
Summary Background The association between tapeworm infection and equine colic is established, but gaps remain regarding specific colic types. Objectives To assess the relationship between tapeworm test results and equine colic types: The study aimed to determine if ileocaecal disorders (IC) are more frequently associated with Anoplocephala spp ...
K. L. Adamasky, K. Drozdzewska, P. Schmitz, N. Peczak, K. L. Lightbody, J. B. Matthews, M. K. Nielsen, R. Merle, G. von Samson‐Himmelstjerna, H. Gehlen   +9 more
wiley   +1 more source