Results 91 to 100 of about 43,372 (134)
Intestinal Epithelial Memory: From Inflammatory Imprinting to Metabolite‐Shaped Immune Tolerance
ABSTRACT Intestinal epithelial cells are rapidly renewing barrier cells that maintain compartmentalization between the luminal environment and the mucosal immune system through epithelial transport, antimicrobial defense, secretory programs, and cytokine‐mediated communication.
Wenjing Yang, Tianming Yu, Yingzi Cong
wiley +1 more source
SLC3A1 Mitigates Ferroptosis and Promotes Enzalutamide Resistance in Prostate Cancer
SLC3A1 is a promising therapeutic target for advanced prostate cancer. ABSTRACT Prostate cancer (PCa) remains a leading cause of cancer‐related mortality in aging male, with resistance to enzalutamide (Enza) representing a major therapeutic challenge. This study identifies SLC3A1 as a key driver of Enza resistance.
Peng Liu +5 more
wiley +1 more source
ABSTRACT Background and Aims Earlier trials of advanced treatments indicated for moderately to severely active Crohn's disease used predominantly re‐randomized induction responder designs, whereas newer treatments were evaluated using treat‐through designs.
Christopher Ma +9 more
wiley +1 more source
ABSTRACT Background Monitoring strategies for patients with inflammatory bowel disease (IBD) in remission vary widely in clinical practice, reflecting limited evidence and a lack of consensus. With increasing numbers of patients living long term with IBD, there is a need for rational, clinically meaningful approaches to remission‐phase monitoring ...
Johan Burisch +42 more
wiley +1 more source
Neoplasias mamárias em cadelas e gatas
Dissertação de Mestrado Integrado em Medicina VeterináriaO estudo das neoplasias mamárias tem um elevado interesse clínico e científico pois além de constituírem uma das neoplasias mais frequentes nas cadelas e nas gatas, muitos dos resultados obtidos ...
Pinto, Rita Mafalda Marques de Oliveira
core +2 more sources
The Evolution of Medications for Obesity Management
ABSTRACT This narrative review provides an overview of progress in the development of obesity medications, including a synthesis of data describing the efficacy and safety of currently available agents and emerging therapeutic options. Historically, many obesity medications have been withdrawn from the market due to safety concerns.
Jaskirath Gill, Priya Sumithran
wiley +1 more source
Se comparan en este estudio los perfiles lipídicos de una población normal de 100 personas con los de 111 afectados de neoplasias diversas. En todos los casos se trataba exclusivamente de varones.
Fernández Rippe, Mª Luisa
core
Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
Plasticité et reprogrammation des cellules intestinales
Les cellules endocrines pancréatiques et intestinales partagent de nombreuses caractéristiques moléculaires, cellulaires et fonctionnelles.Particulièrement, leur différenciation repose sur des programmes génétiques similaires contrôlés par le facteur de ...
GRADWOHL, Gérard, BEUCHER, Anthony
core
Prostate Cancer Development, Progression, and Therapy
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source

