Results 41 to 50 of about 43,372 (134)

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source

Tumor carcinoide del apéndice cecal: cuando un hallazgo incidental modifica drásticamente el pronóstico y tratamiento del paciente

Revista Colombiana de Gastroenterología, 2017
Introducción: la apendicectomía es un procedimiento ampliamente utilizado en todo el mundo, bien sea como consecuencia de signos y síntomas sugestivos de apendicitis aguda o como resección profiláctica.
María Carolina Díaz Rivera, Kenny Buitrago Toro, Pablo Gonzales   +2 more
doaj  

Delivery mode and maternal health conditions before and after childbirth: A population‐based cohort study from Estonia

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Cesarean section is associated with higher rates of chronic health conditions and pregnancy‐related complications, whereas vaginal delivery is more commonly linked to pelvic floor and perineal complications. These findings emphasize the need for individualized decision‐making and thorough counseling about the risks and benefits of each delivery method.
Katrin Täär, Helle Karro, Merli Saare, Reedik Mägi, Estonian Biobank Research Team, Andres Metspalu, Lili Milani, Tõnu Esko, Mait Metspalu, Mari Nelis, Georgi Hudjashov, Andres Salumets, Triin Laisk, Maire Peters   +13 more
wiley   +1 more source

Enfermedad autoinmune y neoplasias [PDF]

, 2008
L a asociación entre enfermedades autoinmunes y un mayor riesgo de desarrollar neoplasias es aún controvertida. La impresión general es que en pacientes con lupus y artritis reumatoide existe un incremento en el riesgo relativo de desarrollar neoplasias ...
Betancur Restrepo, Bibiaana, Ramírez Gómez, Luis Alberto, Arias, Ximena, Villegas, Johanna, Vásquez Duque, Gloria, Cárdenas González, Juan Fernando, Uribe Uribe, Oscar   +6 more
core   +1 more source

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu, Johannes Reiner, Franz Hofmann, Azam Salari, Ursula Seidler   +4 more
wiley   +1 more source

Organoides intestinales murinos: obtención, manipulación y conservación

, 2021
Los organoides intestinales son estructuras multicelulares tridimensionales que poseen un poder replicativo ilimitado natural. Están constituidos por células madre que se diferencian a distintos tipos celulares y recrean en buena medida las ...
Puré audiovisual, Pagotto, Romina, Bollati-Fogolín, Mariela, Daghero, Hellen   +3 more
core   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

GLP‐1 Receptor Agonists Post‐Bariatric Surgery (GRABS) Trial: Rationale, Design and Baseline Characteristics

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims No studies have investigated the synergistic effectiveness of Glucagon‐Like Peptide 1 Receptor Agonists (GLP1RAs) in patients with persistent obesity following bariatric surgery. The GLP‐1 Receptor Agonists Post‐Bariatric Surgery (GRABS) Trial aims to investigate the effectiveness of tirzepatide (TRZ) versus standard of care (SOC) after ...
J. M. Samuels, C. R. Williams, M. B. Patel, W. H. Self, L. M. Funk, C. Roumie, M. D. Spann, C. J. Northup, F. Ye, R. Irlmeier, I. Sohn, Y. Zhu, K. Niswender   +12 more
wiley   +1 more source

Determinación de subtipos tumorales basales en neoplasias mamarias caninas

, 2017
En la mujer, la evaluación de las neoplasias mamarias contempla en la actualidad, la determinación por inmunomarcación de diferentes proteínas que brindan una base para un algoritmo diagnóstico de subtipos tumorales: Basales, luminales tipo A, luminales
Barrios, Mauricio Martín
core