China Anti-Cancer Association guideline for diagnosis and treatment of neuroendocrine neoplasm (2022 edition) [PDF]
Neuroendocrine neoplasm (NEN) is a kind of rare tumor that originated from peptidergic neurons and neuroendocrine cells, which has neuroendocrine differentiation and expresses neuroendocrine markers.
Society of Neuroendocrine Neoplasm of China Anti-Cancer Association
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Clinical significance of diagnostic laparoscopy on precision staging in advanced gastric cancer [PDF]
Gastric cancer is the leading cause of cancer-related deaths in human. More than 70% patients present with advanced gastric cancer or with metastasis in clinic.
NIE Mingming, ZHU Zhenggang
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Anal Dysplasia Among Patients With Multiple Human Papillomavirus Anal Lesions: Mosaic or Homogeneity? [PDF]
Purpose Anal dysplasia is caused by chronic infection with the human papillomavirus and exposes to the risk of anal cancer. The aim of this study was to evaluate the distribution of dysplasia anal grade among patients operated on for multiple anal ...
Emilie Lafferre+6 more
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Methotrexate-induced toxicities in children with malignancy: a systematic review and meta-analysis [PDF]
Objective: Methotrexate (MTX) is an anticancer and anti-inflammatory drug widely used to treat various diseases. Some patients are more susceptible to toxicity, some show resistance to chemotherapy. The most conducted studies have investigated the effect
S. Gharibi+3 more
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Introduction: Osimertinib is an oral, third-generation, irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that selectively inhibits both EGFR-TKI–sensitizing and EGFR T790M resistance mutations.
Haifeng Qin+5 more
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MALAT1 expression is associated with aggressive behavior in indolent B-cell neoplasms
MALAT1 long non-coding RNA has oncogenic roles but has been poorly studied in indolent B-cell neoplasms. Here, MALAT1 expression was analyzed using RNA-seq, microarrays or qRT-PCR in primary samples from clinico-biological subtypes of chronic lymphocytic
Elena María Fernández-Garnacho+17 more
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Solid Pseudopapillary Neoplasm of the Pancreas: Unfolding an Intriguing Condition
Pancreatic cancer is one of the most lethal malignant neoplasms, with a 1-year survival rate after diagnosis of 24%, and a 5-year survival rate of only 9%. While this illustrates the behavior of its main histologic type – ductal adenocarcinoma, there are
Manuel António Alves Cruz+3 more
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Objectives: We sought to identify leukemia-associated immunophenotypes (LAIPs) in 50 acute myeloid leukemia (AML) patients at diagnosis using an eight-color multiparameter flow cytometry (MFC) panel and to detect if they showed any alteration in relapsed/
Hadeer Mohamed Rasheed+4 more
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Metachronous Intraductal Papillary Neoplasm of the Bile Duct and Intraductal Papillary Mucinous Neoplasm of the Pancreas in a Patient Diagnosed With Mucinous Adenocarcinoma. [PDF]
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare biliary tumor, which shares some radiologic and histologic similarities with pancreatic intraductal papillary mucinous neoplasm (IPMN).
Brennan, Gregory T, Lee, John G
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Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target [PDF]
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy for which there is still no effective B therapy.
Abate F.+30 more
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