Results 51 to 60 of about 1,272,565 (330)

Combined laparoscopic spleen-preserving distal pancreatectomy and islet autotransplantation for benign pancreatic neoplasm.

open access: yesWorld Journal of Gastroenterology, 2014
AIM To evaluate the safety and feasibility of laparoscopic spleen-preserving distal pancreatectomy (LSPDP) with autologous islet transplantation (AIT) for benign tumors of the pancreatic body-neck.
G. Balzano   +9 more
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Evading Capture by Residual Disease Monitoring: Extramedullary Manifestation of JAK2 V617F-Positive Primary Myelofibrosis After Allogeneic Stem Cell Transplantation

open access: yesCase Reports in Hematology, 2015
Monitoring of the JAK2 V617F allele burden in myeloproliferative neoplasms after allogeneic stem cell transplantation is useful to determine levels of residual disease and has the potential to detect early relapse and guide subsequent clinical ...
S. Langabeer   +5 more
semanticscholar   +1 more source

Measurable (Minimal) Residual Disease in Myelodysplastic Neoplasms (MDS): Current State and Perspectives

open access: yesCancers
Myelodysplastic Neoplasms (MDS) have been traditionally studied through the assessment of blood counts, cytogenetics, and morphology. In recent years, the introduction of molecular assays has improved our ability to diagnose MDS. The role of Measurable (minimal) Residual Disease (MRD) in MDS is evolving, and molecular and flow cytometry techniques have
Linsheng Zhang   +5 more
openaire   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Hierarchical Phenotyping and Graph Modeling of Spatial Architecture in Lymphoid Neoplasms [PDF]

open access: yesarXiv, 2021
The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the first to hybridize local and global graph methods to profile orchestration and interaction of cellular components.
arxiv  

Automatic Detection of Blue-White Veil and Related Structures in Dermoscopy Images [PDF]

open access: yesComputerized Medical Imaging and Graphics 32 (2008) 670-677, 2010
Dermoscopy is a non-invasive skin imaging technique, which permits visualization of features of pigmented melanocytic neoplasms that are not discernable by examination with the naked eye. One of the most important features for the diagnosis of melanoma in dermoscopy images is the blue-white veil (irregular, structureless areas of confluent blue ...
arxiv   +1 more source

MDNet: A Semantically and Visually Interpretable Medical Image Diagnosis Network

open access: yes, 2017
The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods.
McGough, Mason   +4 more
core   +1 more source

Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer.

open access: yesJAMA Oncology, 2019
Importance Adjuvant chemotherapy in patients with stage III colon cancer prevents recurrence by eradicating minimal residual disease. However, which patients remain at high risk of recurrence after completing standard adjuvant treatment cannot currently ...
J. Tie   +23 more
semanticscholar   +1 more source

MRI Intracranial Neoplasm Localization Using Convolution Neural Network Based Residual Block ResUnet: A Systematic Approach

open access: yesInternational Journal of Electrical and Electronics Research, 2023
Analysis of intracranial neoplasm using multimodal MR images requires accurate and automatic segmentation. However, manually classifying tumors with similar structures or appearances in magnetic resonance imaging (MRI) with similar anatomy or appearances is more challenging, requiring experience to detect brain tumors.
Dr. G N Keshava Murthy   +4 more
openaire   +1 more source

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