Results 121 to 130 of about 1,358,658 (287)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Assessment of Iris Neoplasms

, 1956
F. W. Law, Peter Hansell
openalex   +1 more source

Case of Malignant Neoplasm of the Larynx. [PDF]

, 1911
P. Watson Williams
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

COVID-19, inflammatory cytokines, and digestive system cancers: a bidirectional Mendelian study and mediation analysis. [PDF]

Discov Oncol
Liang Y, Xiao W, Deng B, Chen Q.
europepmc   +1 more source

A Moot Thyroid Neoplasm

, 1958
Joseph A. Buckwalter, Carleton D. Nordschow   +1 more
openalex   +2 more sources

A Case of Laryngeal Neoplasm [PDF]

, 1914
W. Jobson Horne
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Thyroid disease and breast cancer, benign breast neoplasm: a two-sample Mendelian randomization study. [PDF]

BMC Womens Health
Wang B, Ling Y, Zhang H, Liu Y, Yuan J, Zhang Y, Yang M.   +6 more
europepmc   +1 more source

Induction of mammary neoplasms in the ACI rat by 430-keV neutrons, X-rays, and diethylstilbestrol [PDF]

, 1982
Chmelevsky, D., Holtzman, S., Kellerer, Albrecht M., Shellabarger, C. J., Stone, J. P.   +4 more
core   +1 more source