Results 141 to 150 of about 704,490 (345)
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
NEOPLASMS OF THE BLOOD-LYMPH-VASCULAR SYSTEM WITH SPECIAL REFERENCE TO ENDOTHELIOMAS
D. Schuyler Pulford
openalex +2 more sources
A NEOPLASM OF MONOCYTES OF MICE AND ITS RELATION TO SIMILAR NEOPLASMS OF MAN [PDF]
J. Fürth
openalex +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian+12 more
wiley +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Recurrent KRAS mutations in papillary renal neoplasm with reverse polarity
Khaleel I. Al-Obaidy+10 more
semanticscholar +1 more source