Results 81 to 90 of about 601,571 (336)

Moments of a neoplasm

Human Pathology, 2008
During my long career as a practicing pathologist in a university hospital, I have only occasionally met patients sitting at the opposite side of the microscope at my desk. Those of you who have experienced similar situations know that the awkwardness starts when the patient enters the room.
openaire   +4 more sources

Evaluation of Relationship Between Demographics and Dental Status in a Defined Group of Iranian Paediatric Patients Undergoing Cancer Therapy [PDF]

Journal of Clinical and Diagnostic Research, 2015
Context: Cancer is a major cause of death in children under 15 years of age. Aims: This study aimed to evaluate relationship between demographics and dental status in a defined group of Iranian paediatric patients undergoing cancer therapy. Settings
Hamed Mortazavi, Maryam Tashvighi, Morteza Azizian, Hamid Reza Khalighi, Siamak Sabour, Amir Movahhedian, Maryam Baharvand   +6 more
doaj   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

Innocuous presentation of low-grade mucoepidermoid carcinoma of the palate

Journal of Indian Academy of Oral Medicine and Radiology, 2020
Mucoepidermoid carcinoma (MEC) is a malignant epithelial tumor and is the most common minor salivary gland neoplasm. The initial presentation of this pathology can resemble benign lesions and can be misleading.
Thilak T John, Manisha M Khorate, Nivedita Chinam, Poonam R Sawant   +3 more
doaj   +1 more source

Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat [PDF]

, 2017
Case summary A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE).
Fowkes, R C, Garden, O A, Heaps, L A, Lipscomb, V J, Martineau, H, Priestnall, S L, Scudder, C J, Steinbach, S M L, Szladovits, B   +8 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Pterygium: degeneration, exuberant wound healing or benign neoplasm?

Universa Medicina, 2016
Pterygium is a condition characterized by the encroachment of a fleshy triangle of conjunctival tissue into the cornea. Despite various studies, the pathogenesis of pterygium remains unclear.
Nurbuanto Tradjutrisno
doaj   +1 more source

Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]

, 2010
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
core   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source