Results 81 to 90 of about 1,351,716 (308)

Co-occurrence of myeloid neoplasm and plasma cell neoplasm

, 2022
Co-occurrence of myelodysplastic syndrome (MDS) and plasma cell neoplasm in patients with no history of chemo and/or radiotherapy is rarely reported. Herein, we report a case of a female in her seventieth decade of life who was referred to the hospital ...
Jum’ah, Husam, Husam Jumah, Salman Ayub, Ayub, Salman, Yan Wang, Yan Wang, Husam Jum’ah, Salman Ayub, Husam Jum’ah, Wang, Yan   +9 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Radon and Neoplasms

Toxics, 2023
Radon is a carcinogenic factor, but the effects of the potential carcinogenicity of radon progeny on the human body during the prenatal period have not yet been explored. Based on data regarding the half-lives of radon-222 and radon-220 and their progeny, this paper considers their potential effects on the human body in the prenatal period.
openaire   +3 more sources

Diagnosis of Thyroid Neoplasm-Associated Dermatomyositis in Ethiopian Woman [PDF]

Gebrehiwot Lema Legese,1 Yeabsira Aklilu Tesfaye,1 Eleni Ayele,1 Desalew Getahun Ayalew,1 Aron Girma Abebaw,1 Tiruzer Bekele Gurji,2 Abilo Tadesse1 1Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University ...
Gurji TB, Tadesse A, Ayalew DG, Abebaw AG, Tesfaye YA, Legese GL, Ayele E   +6 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Imaging Findings of Primary Angiomyolipoma of the Pancreas: A Case Report

대한영상의학회지, 2017
Angiomyolipoma (AML), a part of a family of mesenchymal tumors, is a common fat-containing solid neoplasm. Kidney and liver are the main sites of AML; rarely, primary pancreatic AML has also been reported. Here, we present a case of pathologically proven
Hye Hee Kim, Dong Hee Park
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A Retrospective Study of Patients Presenting with Neck Masses to a Tertiary Care Center, Jeddah, Saudi Arabia

Electronic Physician, 2019
Background: Studying the prevalence of different types of neck masses can enhance the appropriate and timely diagnosis of the etiology of a neck mass, which is critical in maintaining good prognosis. However, there is a paucity of studies in Saudi Arabia
Majed Nasser Alnefaie, Yousuf AlQurashi, Asalh Tallat Saeedi, Abdullah Ahmed Alamri, Mohammed Algethami, Wejdan Baabdullah, Adel Almaymuni, Mazin Merdad   +7 more
doaj   +1 more source

Atypical fibroxanthoma arising in a tracheostomy scar: A rare cicatricial neoplasm

, 2019
Dear Editor, Atypical fibroxanthoma (AFX) is a cutaneous neoplasm that classically occurs in heavily sun‐damaged skin on the head and neck of elderly patients.1 We report the case of a 70‐year‐old man who presented with a 1‐year history of a slowly ...
Byth, Lachlan A, Lachlan A Byth, Strutton, Geoffrey M, Geoffrey M Strutton   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source