Results 81 to 90 of about 1,272,186 (267)
Cutaneous CD4+/ CD56 hematodermic neoplasm
, 2011 CD4+/CD56+ hematodermic neoplasm, formerly known as blastic NK cell lymphoma, is a rare and aggressive neoplasm with a high incidence of cutaneous involvement, risk of leukemic dissemination and poor prognosis.
Kavala, Mukaddes +4 more
core
Socio-Demographic Characteristics of Study Subjects by Colorectal Neoplasm Staging.
, 2013 Note: AJCC = American Joint Committee on Cancer*Significant difference between colorectal neoplasm staging (except unknown stage)by One-Way ANOVA†Significant difference between colorectal neoplasm staging (except unknown stage)by Chi-square Test ...
Dora L. W. Kwong (166235) +3 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Poral neoplasm with combined sebaceous and apocrine differentiation
, 1998 Poromas have been considered the hallmark of benign eccrine neoplasms. The literature describes six cases of poroma differentiating toward apocrine and sebaceous lineage.
A. Coggi, R. Gianotti, E. Alessi
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Immunophenotypic patterns in precursor T-cell neoplasm
, 2007 T-cell lymphoproliferative disorders are a heterogeneous group of lymphoid neoplasm that can mimic both benign conditions and non-hematopoietic tumors. In routine clinical practice, morphology and immunophenotyping forms the basis of their diagnosis.
Gupta, R. +3 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Microsatellite instability in ovarian neoplasm.
, 1997 Microsatellite instability in ovarian ...
Dionigi A +10 more
core
, 2017 Serous cystic neoplasms of the pancreas are rare exocrine pancreatic neoplasms, most of which are benign and do not communicate with the pancreatic duct.
Yohei Kawashima +11 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source