Results 121 to 130 of about 74,828 (311)

Performance of Magnetic Resonance Imaging-based Permeability Indices for Preoperative Glioma Grading [PDF]

open access: yesJournal of Basic Research in Medical Sciences
Introduction: Due to the inherent limitations of histopathology as the gold standard method for glioma grading, in recent years, alternative methods, including methods based on imaging data, have been proposed for better glioma grading.
Sina Alikhani, Seyed Salman Zakariaee
doaj  

In silico Identification of microRNAs Differentially Expressed in Prostate Cancer and Related to Tumor Aggressiveness

open access: yesBiomedical and Biotechnology Research Journal
Background: Prostate cancer (PCa) remains a major clinical challenge due to the limited ability of current diagnostic tools to distinguish indolent from aggressive tumors.
Fernando Antonio Bergez-Hernández   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

An incidental finding of low‐grade appendiceal mucinous neoplasm during cesarean section: A case report [PDF]

open access: gold, 2019
Eisuke Inubashiri   +7 more
openalex   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions

open access: green, 2020
Kohei Fujikura   +27 more
openalex   +2 more sources

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