Results 141 to 150 of about 2,228,127 (334)

Low-grade appendiceal mucinous neoplasm [PDF]

, 2020
openaire   +2 more sources

The additional value of CT images interpretation in the differential diagnosis of benign vs. malignant primary bone lesions with 18F-FDG-PET/CT [PDF]

, 2018
Objective: To evaluate the value of a dedicated interpretation of the CT images in the differential diagnosis of benign vs. malignant primary bone lesions with 18fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT ...
Bode, B., Exner, U., Hany, T., Hodler, Juerg, Mende, K., Strobel, K., Stumpe, K., Veit-Haibach, P., von Schulthess, G.   +8 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Differentiation grade as a risk factor for lymph node metastasis in T1 colorectal cancer

DEN Open
Objectives Japanese guidelines include high‐grade (poorly differentiated) tumors as a risk factor for lymph node metastasis (LNM) in T1 colorectal cancer (CRC).
Osamu Shiina, Shin‐ei Kudo, Katsuro Ichimasa, Yuki Takashina, Yuta Kouyama, Kenichi Mochizuki, Yuriko Morita, Takanori Kuroki, Shun Kato, Hiroki Nakamura, Shingo Matsudaira, Masashi Misawa, Noriyuki Ogata, Takemasa Hayashi, Kunihiko Wakamura, Naruhiko Sawada, Toshiyuki Baba, Tetsuo Nemoto, Fumio Ishida, Hideyuki Miyachi   +19 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Predicting the histological grade of hepatocellular carcinoma based on dynamic radiomics

Asian Journal of Surgery
Background: Radiomics studies for preoperative prediction of histological grade of hepatocellular carcinoma (HCC) have primarily concentrated on static features, thereby overlooking the dynamic changes in radiomics features across different phases ...
Rui Zhang, Yao Wang, Zhi Li, Yushu Shi, Danping Yu, Xue Wen, Feng Chen, Wenbo Xiao, Chencui Huang, Zhan Feng   +9 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Classification and Grading of Canine Mammary Tumors

Veterinary Pathology-Supplement, 2011
M. Goldschmidt, L. Peña, R. Rasotto, V. Zappulli   +3 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Association Between Systemic Immune-Inflammatory Index (SII) and Cancer Grading and Staging: Evidence from the Current Scientific Literature

Biology
Background: Accumulating evidence demonstrates that inflammatory responses play a critical role in tumor progression, invasion, and metastasis. In recent years, systemic immune-inflammatory (SII) markers have emerged as valuable tools for evaluating ...
Alessandro Rizzo, Elsa Vitale, Lorenza Maistrello, Kazuki Santa, Matteo Santoni   +4 more
doaj   +1 more source