Results 171 to 180 of about 46,847 (244)

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

Evaluation of Cancer Cell Invasion Ability Based on Electrochemical Impedance. [PDF]

Biosensors (Basel)
Jiang F, Wei M, Chen S, Wang Y, Liu N, Yang N.   +5 more
europepmc   +1 more source

Non‐Enzymatic Destruction of the Extracellular Matrix for Activatable Orthotopic Tumor Treatment and Enhanced Drug Penetration

Advanced Functional Materials, EarlyView.
Supramolecular biomimetic nanoaggregates (HFCu NAs), constructed with fluorinated histidine and copper ions via metal coordination and aromatic packing, exhibit enhanced reactive oxygen species （ROS）generation at tumor sites, which results in stepwise collapse of the extracellular matrix (ECM), affording tumor microenvironment responsive “turn‐on” 19F ...
Hui Wang, Ruxin Feng, Yan Wang, Qian Ma, Di Yuan, Xi Yang, Suying Xu, Tony D. James, Leyu Wang   +8 more
wiley   +1 more source

Dental pulp stem cells express proteins involved in the local invasiveness of odontogenic myxoma [PDF]

Abrahão IJ, Anttila MA, Aresu L, Barker BF, Barros RE, Bast BT, Camenisch TD, Carlos Magno da Costa Maranduba, Coussens LM, Curran S, Day AJ, Demers M, Enegd B, Fernando de Sá Silva, Gaffney J, Garcia JM, Harumi Miyagi SP, Jaeger MMM, Jiang D, Kerkis I, Knudson W, Miura M, Miyagi SP, Márcia Martins Marques, Overall CM, Parks WC, Stern R, Sueli Patricia Harumi Miyagi, Sumi Y, Toole BP, Toole BP, Toole BP, Toole BP, Wang SJ   +33 more
core   +1 more source

Evaluation of Integrin Glycovariants as Biomarkers of Metastasis, Invasion, and Therapy Stratification in Head and Neck Squamous Cell Carcinoma. [PDF]

Cancer Med
Routila E, Salminen S, Mahran R, Toriseva M, Irjala H, Haapio E, Kytö E, Ventelä S, Pettersson K, Routila J, Gidwani K, Leivo J.   +11 more
europepmc   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

A practical approach for the diagnosis and management of pancreatic cystic lesions-the Hong Kong consensus recommendations. [PDF]

Hepatobiliary Surg Nutr
Chatterjee A, Garg R, Chahal P.
europepmc   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Cell crowding activates pro-invasive mechanotransduction pathway in high-grade DCIS via TRPV4 inhibition and cell volume reduction. [PDF]

Elife
Bu X, Ashby N, Vitali T, Lee S, Gottumukkala A, Yun K, Tabbara S, Latham P, Teal C, Chung I.   +9 more
europepmc   +1 more source