Results 151 to 160 of about 98,057 (268)

Radiomic model with SHAP-based interpretability for predicting invasiveness of pure ground-glass nodules: a retrospective study based on high-resolution computed tomography (HRCT) volumetric datasets. [PDF]

J Cardiothorac Surg
Sheng H, Wang R, Zhang G, Dong N, Zhou Y, Wang P, Li K, Bai G.   +7 more
europepmc   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

Advanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar, Daan Vorselen, Jai Prakash   +2 more
wiley   +1 more source

Long-term outcomes and patterns of failure in patients with thymic malignancies treated with surgery and radiation therapy. [PDF]

Cancer
Icht O, Nardi-Agmon I, Thavendiranathan P, Keshavjee S, Agrawal A, Miro JM, Badran O, Liu G, Ye XY, Cho BCJ, Bezjak A, Hope A.   +11 more
europepmc   +1 more source

The Role of Viscoelasticity in Heterogeneous Glioblastoma Stem Cell Invasion in Biomimetic 3‐Dimensional Hydrogels

Advanced Healthcare Materials, EarlyView.
The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine, Arianna Skirzynska, Allysia A. Chin, Julie Audet, Molly S. Shoichet   +4 more
wiley   +1 more source

Sequential invasion assays identify carbonic anhydrase IX as a driver of invasiveness in epithelial triple-negative breast cancer cells. [PDF]

Am J Physiol Cell Physiol
Black PJ, Ball DD, Edwards AD, Macintosh AR, Sakwe NI, Vuong NB, Korolkova OY, Sharma V, Misra S, Sakwe AM.   +9 more
europepmc   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Correction: Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway. [PDF]

J Exp Clin Cancer Res
Hu X, Li YQ, Li QG, Ma YL, Peng JJ, Cai SJ.   +5 more
europepmc   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

MRI radiomics-based approach to predict pituitary neuroendocrine tumor invasiveness. [PDF]

Eur Radiol Exp
Calandrelli R, Tran HE, Boccia E, Oliva E, D'Apolito G, Boldrini L, Mattogno PP, Chiloiro S, Gessi M, Doglietto F, Gaudino S.   +10 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source