Results 131 to 140 of about 99,952 (361)

Multiparametric Classification of Non-Muscle Invasive Papillary Urothelial Neoplasms: Combining Morphological, Phenotypical, and Molecular Features for Improved Risk Stratification [PDF]

open access: gold, 2022
Ivonne A. Montes‐Mojarro   +9 more
openalex   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Laparoscopic Nephroureterectomy with Concomitant Open Bladder Cuff Excision A Single Center Experience

open access: yesUrology Journal, 2012
Purpose: To evaluate the efficacy of laparoscopic nephroureterectomy and open bladder cuff excision for management of upper urinary tract urothelial carcinoma.Materials and Methods: Twenty-two patients with upper urinary tract urothelial carcinoma, who ...
Seyed Amir Mohsen Ziaee   +4 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Cytosolic HMGB1 Expression in Human Renal Clear Cell Cancer Indicates Higher Pathological T Classifications and Tumor Grades

open access: yesUrology Journal, 2013
Purpose: High mobility group box (HMGB) proteins are nuclear nonhistone chromosomalproteins that bend DNA, bind preferentially to distorted DNA structures, and promote the assemblyof site-specific DNA binding proteins.
Koji Mikami   +6 more
doaj  

Uteroplacental apoplexy associated with invasive cervical neoplasm.

open access: yesRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2018
The cervical cancer is the worldwide second neoplasia in women, after the breast cancer. The incidence of invasive carcinoma in pregnancy is 1÷2000 to 1÷10 000 pregnancies. In most of the studies, almost all the patients had microinvasive carcinoma or limited cervical carcinoma at the cervix level.
Anca Daniela, Brăila   +7 more
openaire   +1 more source

A Modified Seroflocculation Reaction in Relationship to Invasive Neoplasms.

open access: yesExperimental Biology and Medicine, 1957
SummaryA method is described for an improved laboratory aid in mass screening for invasive neoplasms. The modification of the described seroflocculation test consisted essentially in heating sera at 64°C for 30 minutes.
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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