Advanced Healthcare Materials, EarlyView.Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
The impact of macrophage infiltration on [18F]FDG PET accuracy in identifying mediastinal and abdominal lymph node metastases: A retrospective cohort study. [PDF]
PLoS OneWei J, Tao W, Yang T, Dong J.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
Collision tumor: a parathyroid adenoma unveiling subclinical widespread breast carcinoma: a case report. [PDF]
J Med Case RepYacoub S +5 more
europepmc +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
The prognostic significance of lymph node metastasis-related genes in pancreatic adenocarcinoma is associated with immune cell infiltration and ferroptosis. [PDF]
Medicine (Baltimore)Shu Q, Liu X.
europepmc +1 more source
Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions
Advanced Healthcare Materials, EarlyView.Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi +7 more
wiley +1 more source
Occult Breast Cancer Diagnosed from a Solitary Scalp Metastasis without Axillary Lymph Node Involvement: A Case Report. [PDF]
Surg Case RepUshio T +7 more
europepmc +1 more source
Geometrical Designs in Volumetric Bioprinting to Study Cellular Behaviors in Engineered Constructs
Advanced Healthcare Materials, EarlyView.Curvature and spatial confinement guide cell behavior in volumetrically printed 3D constructs. Endothelial cells align and spread along specific geometries, while metastatic osteosarcoma cells proliferate independently of structural cues. Label‐free holographic microscopy captures real‐time, long‐term cell–material interactions, highlighting Gel‐PEG's ...
Julia Simińska‐Stanny +3 more
wiley +1 more source
Challenges in Managing Brain Metastases From Merkel Cell Carcinoma in an Immunosuppressed Patient: A Case Report. [PDF]
CureusRebelo F +4 more
europepmc +1 more source