Results 251 to 260 of about 936,810 (386)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Cytology-Radiology Correlation Series: Pancreatic cytopathology. [PDF]

Cancer Cytopathol
Trieu J, Gilman A, Konstantinoff K, Lozano MD, Saieg M.   +4 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary‐like nuclear features

Cancer Cytopathology, 2017
N. Ohori, Raja R Seethala, Y. Nikiforov
semanticscholar   +1 more source

Face to Face With Renal Cell Carcinoma: A Case Report. [PDF]

Cureus
Andrade MA, Caires F, Duarte CC, Santana C, Saldanha C.   +4 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

No Difference in Prognosis between Atypical Intradermal Smooth Muscle Neoplasms and Dermal Leiomyosarcoma: Local Recurrence, Metastasis, and Overall Survival in a Nationwide Cohort of 423 Patients

Kiya Abebe, Mathias Ørholt, E. Bak, Andreas Haahr Larsen, Anne Lene Wagenblast, Grethe Schmidt, David Hebbelstrup Jensen, Michael Mørk Petersen, Anand C. Loya, Sören Daugaard, Mikkel Herly, Jason L. Hornick, Thomas Mentzel, Peter Vester-Glowinski   +13 more
openalex   +1 more source

Clinical relevance of MMP-9 in terms of neoplasm growth, invasion and metastasis in thyroid, breast and colorectal cancer

, 2017
V. Hari Kumar, Omar Bin Hasan
openalex   +2 more sources

An uncommon site for papillary thyroid carcinoma metastasis: a case of breast involvement. [PDF]

World J Surg Oncol
Bains L, Katuri UK, Polisetty C, Lal P, Singh M.   +4 more
europepmc   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source