Results 41 to 50 of about 3,165 (219)

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Incidence and risk factors of gastrointestinal neuroendocrine neoplasm metastasis in liver, lung, bone, and brain: A population‐based study

open access: yesCancer Medicine, 2019
Background Neuroendocrine neoplasm is a rare solid tumor. Metastatic pattern of the gastrointestinal neuroendocrine neoplasm (GI‐NEN) has not been fully explored.
Zhibo Zheng   +6 more
doaj   +1 more source

Solitary pancreatic renal cell carcinoma metastasis

open access: yesAutopsy and Case Reports, 2018
Pancreatic metastases are rare; they account for only 2% of all pancreatic malignancies and usually occur when associated with a disseminated metastatic disease.
Miguel Nogueira   +4 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

NeoUNet: Towards accurate colon polyp segmentation and neoplasm detection [PDF]

open access: yesarXiv, 2021
Automatic polyp segmentation has proven to be immensely helpful for endoscopy procedures, reducing the missing rate of adenoma detection for endoscopists while increasing efficiency. However, classifying a polyp as being neoplasm or not and segmenting it at the pixel level is still a challenging task for doctors to perform in a limited time.
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Paratesticular metastasis from colorectal adenocarcinoma presenting as hydrocele: a rare case report and literature review

open access: yesFrontiers in Oncology
Colorectal cancer, with the liver being the most common site of distant metastasis, followed by the lungs and bones. Although reports of metastasis to the testis exist, paratesticular metastasis is extremely rare.
XiaoJun Huang   +4 more
doaj   +1 more source

Aggressive Behaviour of Metastatic Melanoma in a Patient with Neurofibromatosis Type 1

open access: yesCase Reports in Surgery, 2015
Malignant melanoma is a common skin neoplasm bearing poor prognosis when presenting with metastases. Rarely melanoma metastases present without an identifiable primary cutaneous lesion despite exhaustive workup.
Robert W. Foley   +3 more
doaj   +1 more source

Higher order organizational features can distinguish protein interaction networks of disease classes: a case study of neoplasms and neurological diseases [PDF]

open access: yesarXiv, 2022
Neoplasms (NPs) and neurological diseases and disorders (NDDs) are amongst the major classes of diseases underlying deaths of a disproportionate number of people worldwide. To determine if there exist some distinctive features in the local wiring patterns of protein interactions emerging at the onset of a disease belonging to either of these two ...
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

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