Results 61 to 70 of about 774,272 (298)

A rare case of an intramedullary metastasis of a myxopapillary ependymoma [PDF]

, 2019
Ependymoma; Intramedullary; MetastasisEpendimoma; Intramedular; MetástasisEpendimoma; Intramedular; MetàstasiBackground: Myxopapillary ependimoma (MPE) is a benign slow-growing tumor, and it has been designated histologically as a Grade I neoplasm ...
Cicuendez López Ocaña, Marta, Bescós Cabestre, Agustí, Martínez Ricarte, Francisco Ramón, Cordero Asanza, Esteban Xavier, Fonseca, Lino, Martinez Saez, Elena Antima   +5 more
core   +1 more source

[10]-gingerol is a potent inhibitor of breast cancer metastasis in vivo

, 2021
sem informação32322222315th International Biennial Congress of the Metastasis Research ...
Tomasin, Rebeka, Fernandes, Joao Batista, Pouliot, Normand, Ling, Phoebe, Vieira, Paulo Cezar, da Silva, James Almada, Moreno Martin, Ana Carolina B., de Araujo, Heloisa S. S., Cominetti, Marcia R.   +8 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Prostatic cancer with parotid metastases

Urology Case Reports
Parotid metastases from prostate cancer are unusual. The distinction between a primary parotid neoplasm and a metastasis is important clinically, because the management of metastasis in castration resistant prostate cancer is different.We report a rare ...
Hanane Inrhaoun, Ibrahim Elghissassi, Sara Naciri, Salma Najem, Sihame Lkhoyaali, Ahmed Ibrahimi, Tsioukaka Gray, Rachida Latib, Saber Boutayeb, Hind Mrabti, Hassan Errihani   +10 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition [PDF]

, 2013
Though clinicians can predict which patients are at risk for developing metastases, traditional therapies often prove ineffective and metastatic disease is the primary cause of cancer patient death; therefore, there is a need to develop anti-metastatic ...
Adam I. Marcus, Songli Xu (457629), Anapatricia Garcia (457628), Paula M. Vertino (457631), Klymkowsky, Michael, Doris R Powell, Marcus Adam I., Vertino, PM, Anapatricia Garcia, Shivendra Singh (457632), Singh Shivendra, Yang, Zhen, Doris R. Powell (457630), Paula M Vertino, Garcia Anapatricia, Vertino Paula M., Singh, Shivendra, Paula M. Vertino, Adam I Marcus, Marcus, Adam I., Garcia, A, Powell, DR, Shivendra Singh, Singh, S, Zhen Yang (107412), Powell, Doris R., Zhen Yang, Yang, Z, Yang Zhen, Vertino, Paula M., Songli Xu, Xu, S, Garcia, Anapatricia, Xu, Songli, Doris R. Powell, Zhen Yang, Adam I. Marcus (457633), Powell Doris R., Marcus, AI, Xu Songli   +39 more
core   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Clinicopathologic characteristics of thymic clear cell carcinoma: a case report with literature review

Journal of Cardiothoracic Surgery, 2023
Background Thymic clear cell carcinoma is a rare mediastinal neoplasm, with only 25 reported cases to date. We report a case of a 45-year-old man with thymic clear cell carcinoma.
Zuxuan Zhao, Qingpeng Zeng, Jiangtao Li, Shan Zheng   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Malignant melanocytic neoplasm of pancreas with liver metastasis: Is it malignant melanoma or clear cell sarcoma?

, 2017
Malignant melanocytic neoplasm, usually seen in soft tissues, is rare in a visceral location and presents as a diagnostic dilemma. We present a case of pancreatic malignant melanocytic neoplasm with liver metastasis. A 58-year-old man presented with left
Sam Varghese George, Raju Titus Chacko, Thomas Alex Kodiatte, Banumathi Ramakrishna   +3 more
core   +1 more source