Results 61 to 70 of about 310,430 (355)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

A rare case of solitary fibrous tumor of the temporal region: 7-year-follow-up clinical-radiographic evaluation and literature review

Oral and Maxillofacial Surgery Cases, 2022
Solitary fibrous tumor is a rare spindle-cell neoplasm of mesenchymal origin. In head and neck region, the tumors present slow-growing masses, often with local compressive symptoms. Although it is generally benign, malignant variants have been identified.
Ugo Consolo, Francesco Diamante, Attilio Carlo Salgarelli, Pierantonio Bellini   +3 more
doaj   +1 more source

Recent advances in managing differentiated thyroid cancer [PDF]

, 2018
The main clinical challenge in the management of thyroid cancer is to avoid over-treatment and over-diagnosis in patients with lower-risk disease while promptly identifying those patients with more advanced or high-risk disease requiring aggressive ...
Durante, Cosimo, Filetti, Sebastiano, Grani, Giorgio, Lamartina, Livia   +3 more
core   +2 more sources

[Radiofrequency ablation for lung neoplasms with isolated postsurgical local 
recurrences or metastases of non-small cell lung cancer].

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2014
Primary lung cancer is one of the most common malignancies worldwide. Surgical resection remains the first choice for the treatment of early stage non-small cell lung cancer (NSCLC). Relapse after surgery sharply reduces the patient's life expectancy. This relapse is referred to as isolated postsurgical local recurrences or metastases (IPSLROM), which ...
Baodong Liu, Xiuyi Zhi, Kun Qian, Lei Liu, Mu Hu, Yuanbo Li   +5 more
openaire   +4 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Invasive head and neck cutaneous squamous cell carcinoma: clinical and histopathological characteristics, frequency of local recurrence and metastasis [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: squamous cell carcinoma is the second most common type of skin malignancy and may evolve to regional lymph node and distant metastases. OBJECTIVE: The objective of this study was to evaluate patients with head and neck cutaneous squamous ...
Luiza Vasconcelos, Juliana Carneiro Melo, Hélio Amante Miot, Mariângela Esther Alencar Marques, Luciana Patricia Fernandes Abbade   +4 more
doaj   +1 more source

Prognostic factors for hepatocellular carcinoma recurrence.

World Journal of Gastroenterology, 2014
The recurrence of hepatocellular carcinoma, the sixth most common neoplasm and the third leading cause of cancer-related mortality worldwide, represents an important clinical problem, since it may occur after both surgical and medical treatment.
A. Colecchia, R. Schiumerini, A. Cucchetti, M. Cescon, Martina Taddia, G. Marasco, D. Festi   +6 more
semanticscholar   +1 more source

Complete mesocolic excision does not increase short-term complications in laparoscopic left-sided colectomies : a comparative retrospective single-center study [PDF]

, 2019
Background: Since the implementation of total mesorectal excision (TME) in rectal cancer surgery, oncological outcomes improved dramatically. With the technique of complete mesocolic excision (CME) with central vascular ligation (CVL), the same surgical ...
Claeys, Donald, Defoort, Barbara, Dewulf, Maxime, Kalmar, Alain, Muysoms, Filip, Pletinckx, Pieter, Vandenberk, Bert   +6 more
core   +2 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Radiofrequency ablation for recurrent hepatocellular carcinoma: 10-year outcomes of local tumor progression vs intrahepatic distant recurrence

Insights into Imaging
Objectives To compare the long-term outcome of radiofrequency ablation (RFA) for local tumor progression (LTP) vs intrahepatic distant recurrence (IDR) in recurrent hepatocellular carcinoma (rHCC), including cases with repeated LTP. Materials and methods
Huan-ling Guo, Jia-qian Yao, Xin Zheng, Tong-yi Huang, Xiao-er Zhang, Rui Zhang, Wen-xin Wu, Xiao-yan Xie, Ming Xu   +8 more
doaj   +1 more source