Results 81 to 90 of about 181,578 (305)

Predictive value of nodal metastases on local recurrence in the management of differentiated thyroid cancer. Retrospective clinical study.

open access: yes, 2013
Background: The significance of nodal metastases, very common in papillary thyroid cancer, and the role of lymph node dissection in the neoplasm management, are still controversial.
PASQUALI, Daniela   +10 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Surgical and therapeutic strategy of recurrent malignant gliomas in intractable location

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective Recurrent malignant gliomas often violate important neurological function parts or deep brain structures due to tumor invasion, further increasing the difficulty of reoperation and treatment.
Yun⁃tao LU   +7 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Rapid Local Recurrence of Breast Myoepithelial Carcinoma Arising in Adenomyoepithelioma: A Case Report

open access: yes대한영상의학회지, 2020
Adenomyoepithelioma (AME) is a rare breast neoplasm composed of both epithelial and myoepithelial cells with biphasic proliferation. Although most AMEs are benign, malignant transformation of either or both cellular components may occur.
Mo In Ha, Bo Kyoung Seo, Jung Woo Choi
doaj   +1 more source

Fibromatosis of the Plantar Fascia: Diagnosis and Indications For Surgical Treatment [PDF]

open access: yes, 1999
Plantar fibromatosis is a rare, benign lesion involving the plantar aponeurosis. Eleven patients (13 feet) underwent 24 operations, including local excision, wide excision, or complete plantar fasciectomy. Clinical results were evaluated retrospectively.
Lienemann, Andreas   +4 more
core   +1 more source

The effect of local anesthetic technique on breast cancer-related outcomes: a systematic review

open access: yes, 2021
Apesar de ser uma importante abordagem para o tratamento do câncer de mama, a cirurgia pode paradoxalmente favorecer a progressão tumoral, apesar da intenção curativa.
Batista, Arthur Giovane Campos   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Surgical treatment of renal cell carcinoma recurrence at the renal fossa following radical nephrectomy

open access: yesSão Paulo Medical Journal
CONTEXT: Isolated renal cell carcinoma recurrence at the renal fossa is a rare event. This condition occurs in 1 to 2% of radical nephrectomy cases. It is usually seen in postoperative follow-up imaging examinations such as abdominal computed tomography ...
Carlos Márcio Nóbrega de Jesus   +2 more
doaj   +1 more source

Assessment for Risk Factors Associated with Local Recurrence in Chordoma

open access: yes, 2015
Background Chordoma is a rare but locally aggressive malignant neoplasm showing notochordal differentiation. The clinical differential diagnoses can be extensive, and definitive diagnosis often relies on histopathologic evaluation.
Abraham, MD, John A.   +1 more
core  

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