Results 191 to 200 of about 748,361 (308)
Advanced Science, EarlyView.This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao +7 more
wiley +1 more source
Surgical resection and full-thickness skin grafting for sebaceoma extending into the external auditory canal: a case report. [PDF]
J Surg Case RepYoshimura M, Omori M.
europepmc +1 more source
Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis
Advanced Science, EarlyView.A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu +7 more
wiley +1 more source
Gastric Spindle Cell Neoplasm With LMNA::NTRK1 Fusion: A Rare Mimic of Wild-Type GIST. [PDF]
Case Rep SurgSeo Y +4 more
europepmc +1 more source
Advanced Science, EarlyView.Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li +8 more
wiley +1 more source
KAT6B::KANSL1 fusion-positive uterine mesenchymal neoplasm with hybrid endometrial stromal and smooth muscle features: a case report. [PDF]
Front Med (Lausanne)Li Q, Wu M.
europepmc +1 more source