Results 221 to 230 of about 1,271,894 (347)

A Case of Retroperitoneal Desmoid Tumor That Was Difficult to Distinguish from Postoperative Recurrence of Pancreatic Neuroendocrine Neoplasm

Hiroaki Fuji, Masaharu Tada, Hideaki Sueoka, Ikuo Nakamura, Kenjiro Iida, Tomohiro Okamoto, Masayuki Okuno, Ami Kurimoto, Daisuke Shirai, Makoto Yoshida, Hiroshi Kono, Seiko Hirono   +11 more
openalex   +1 more source

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

Prognostic Factors in Neuroendocrine Neoplasms of the Rectum. [PDF]

Cancers (Basel)
Butz F, Müller-Debus CF, Ecseri FG, Mani GS, Akgündüz E, Dukaczewska A, Steinhagen PR, Fehrenbach U, Kunze CA, Jann H, Pratschke J, Dobrindt EM, Mogl MT.   +12 more
europepmc   +1 more source

High-grade and Invasive Intraductal Papillary Mucinous Neoplasm of the Pancreas with STK11 Aberration Having Undergone Pancreatic Resection Three Times for Metachronous Intrapancreatic Recurrences: A Case Report and Review of the Literature

Hideyuki Anan, Shinsuke Koshita, Yoshihide Kanno, Takahisa Ogawa, Hiroaki Kusunose, Toshitaka Sakai, Keisuke Yonamine, Kazuaki Miyamoto, Fumisato Kozakai, Haruka Okano, Kento Hosokawa, Masaya Oikawa, Takashi Tsuchiya, Yutaka Noda, Takashi Sawai, Taito Itoh, Yuko Omori, Toru Furukawa, Kei Ito   +18 more
openalex   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

Congenital solitary neck ulcer as a presentation of Langerhans cell histiocytosis. [PDF]

Skin Health Dis
Abtahi-Naeini B, Derakhshan M, Emamjomeh A, Ghehsareh Ardestani A, Momenzadeh SS, Pourmahdi-Boroujeni M.   +5 more
europepmc   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Slow-Growing Pancreatic Smooth Muscle Tumor Treated with Partial Pancreatectomy: A Case Report. [PDF]

Surg Case Rep
Murase Y, Aikawa M, Miyama Y, Watanabe Y, Takase K, Watanabe Y, Ono H, Okada K, Okamoto K, Koyama I.   +9 more
europepmc   +1 more source

Citrullination of AKT2 Catalyzed by PAD1 Facilitates the Maintenance of Stemness Characteristics of Ovarian Cancer Stem‐Like Cells in Ovarian Cancer

Advanced Science, EarlyView.
PAD1 is upregulated within the CD133+ subset or cisplatin‐resistant ovarian cancer cells, which is positively associated with the upregulation of stemness‐related markers and maintenance of stemness in OCSLCs. Mechanistically, PAD1‐catalyzed AKT2 citrullination at R202 facilitates AKT2 phosphorylation, promoting CEBPβ expression and its binding to the ...
Teng Xue, Xiaoqiu Liu, Chao Song, Shujia Fei, Jian Gu, Yun Han, Jia Xing, Xiaohan Liu, Fei Liang, Paul R Thompson, Xuesen Zhang   +10 more
wiley   +1 more source

Solitary Fibrous Tumor in the Orbit: A Rare Occurrence. [PDF]

Cureus
Sethi J, Chhabra AM, Loiacono AM, Eanelli TR.   +3 more
europepmc   +1 more source