Results 121 to 130 of about 179,703 (257)

Symptom-based staging for logopenic variant primary progressive aphasia [PDF]

Background and purpose Logopenic variant primary progressive aphasia (lvPPA) is a major variant presentation of Alzheimer's disease (AD) that signals the importance of communication dysfunction across AD phenotypes.
Thompson, L., Marshall, C.R., Harding, E., Oxtoby, N.P., Taylor-Rubin, C., Chokesuwattanaskul, A., Stott, J., Wood, O., Kupeli, N., Hardy, C.J.D., Rohrer, J.D.,, Walker, F., Waddington, C., Zimmermann, N., Crutch, S.J., Barker, S., Warren, J.D., Jiang, J., Volkmer, A., Camic, P.M., Brotherhood, E., Taylor, B., Yong, K.X.X., Suarez Gonzalez, A., Kingma, R.   +24 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Neoplasm staging and organ-confined renal cell carcinoma: a systematic review

, 2004
OBJECTIVES: Several TNM staging system editions were published over the years for renal cell carcinoma (RCC). Using a search strategy similar to the one used by the TNM process Subcommittee for "literature watch", we searched MEDLINE with the intent to ...
GALFANO A, ARTIBANI W., NOVARA, GIACOMO, FICARRA, VINCENZO   +3 more
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Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Staging Ajax's suicide /

, 2015
"This volume collects the contributions presented and discussed in the international conference "Staging Ajax's Suicide" held at the Scuola Normale Superiore on 7-9 November 2013.
Ozbek, Leyla,edt, Most, Glenn W.(viaf)108445936, Staging Ajax's Suicide (Conference)(2013 :Scuola normale superiore)   +2 more
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Staging Violence Against Women and Girls: Plays and Interviews

, 2023
Staging Violence Against Women and Girls brings together three contemporary plays that denounce gendered violence, along with interviews with their creators and the practitioners who have staged them in different national contexts.
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Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Factors associated with postoperative recurrence in perforated colorectal cancer: unraveling the high recurrence rate of perforated colorectal cancer

World Journal of Surgical Oncology
Background Perforated colorectal cancer exhibits a higher recurrence rate than non-perforated colorectal cancer; however, the reasons for this difference remain unclear.
Makoto Takagi, Seongcheol Kim, Masaomi Suzuki, Tetsuyoshi Takayama, Hiroshi Asano   +4 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm: challenges and future prospects

, 2017
Amy M Trottier, Sonia Cerquozzi, Carolyn J Owen Division of Hematology and Hematological Malignancies, University of Calgary, Foothills Medical Centre, Calgary, AB, Canada Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare CD4+ CD56+
Trottier AM, Cerquozzi S, Owen CJ
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Classification and staging of retinoblastoma. [PDF]

, 2018
Classifying and staging retinoblastoma is an essential first step when planning how to manage a child with the condition; it also gives important information about prognosis.
Mandeep S Sagoo, Fabian, ID, Reddy, A, Ido Didi Fabian, Sagoo, MS, Ashwin Reddy   +5 more
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