Results 131 to 140 of about 726,328 (344)

The efficacy of endoscopic ultrasonography in local staging of rectal tumors

The Turkish Journal of Gastroenterology, 2012
Belkıs Ünsal, Emrah Alper, Behlül BAYDAR, Mahmut Arabul, Fatih Aslan, Mustafa Çelik, Zafer BUYRAÇ, Serdar AKÇA   +7 more
doaj   +1 more source

Proposal for the applicability of modified Breslow (measured from the basal membrane) as a predictor of survival and sentinel lymph node outcome in patients with cutaneous melanoma

Anais Brasileiros de Dermatologia
Background Cutaneous melanoma is a neoplasm with a high mortality rate and risk of metastases to distant organs. The Breslow micrometric measurement is considered the most important factor for evaluating prognosis and management, measured from the ...
Marcel Arakaki Asato, Francisco Alves Moares Neto, Marcelo Padovani de Toledo Moraes, Juliana Polizel Ocanha-Xavier, Luiz Carlos Takita, Mariangela Esther Alencar Marques, José Cândido Caldeira Xavier-Júnior   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Comprehensive laparoscopic surgical staging of ovarian dysgerminoma in a 13-year-old girl: a case report

, 2008
A case of comprehensive laparoscopic surgical staging for ovarian dysgerminoma in a 13-year-old girl is described. A 20-cm pelvic mass, rising from right adnexum, was incidentally diagnosed, and the patient underwent laparoscopic right salpingo ...
CROMI, ANTONELLA, SIESTO, GABRIELE, UCCELLA, STEFANO, GHEZZI, FABIO, SEVESO, ANNA   +4 more
core  

Vigor of bi-parametric MRI with MR segmentation unity in valuation of UB neoplasm mural invasion

Background The urinary bladder neoplasm is considered the second most frequent kind of neoplasm globally, after prostate cancer. Bladder neoplasm clinical management strategies and prognosis depend on the extent of loco-regional disease.
Fatma Rabee Tony, Ehab Ali Abdel gawad, Sara Mahmoud Ragaee, Gerges Malak Beshreda, Moustafa Magdy Abdel Ghany, Shymaa Shehata Sharqawy   +5 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Ca ovarii (IC, IIC, IIIA, B, C - FIGO): Chemotherapy vs. chemotherapy + radiotherapy [PDF]

Archive of Oncology, 2002
Rudan Ljiljana, Plešinac-Karapandžić Vesna, Marjanov Ivanka, Zoranović Slavica, Petrović-Stupar Sonja, Čolaković Slobodanka, Matijašević Miodrag, Josifovski Jeremija, Mihajlović Branka   +8 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Revised FIGO staging systems for gynecologic malignancies – 2009 update

, 1970
Neoplasm staging system was created to facilitate making diagnoses and planning treatment for cancer patients. Since medical research and practice in the field of oncology have shown explosive growth, the staging of some of the gynecologic cancers did ...
Doniec, Jacek, Zalewski, Kamil, Baranowski, Włodzimierz, Bidziński, Mariusz   +3 more
core