Results 61 to 70 of about 179,703 (257)

The International Association for the Study of Lung Cancer Lung Cancer Staging Project: proposals for the revision of the clinical and pathologic staging of small cell lung cancer in the forthcoming eighth edition of the TNM Classification for Lung Cancer

, 2016
: Introduction Small cell lung cancer (SCLC) is commonly classified as either limited or extensive, but the Union for International Cancer Control TNM Classification of Malignant Tumours seventh edition (2009) recommended tumor, node, and metastasis (TNM)
Nicholson, Andrew G., Chansky, Kari, Van Meerbeeck, Jan, Staging and Prognostic Factors Committee, Advisory Boards, and Participating Institutions, Rami-Porta, Ramón, Eberhardt, Wilfried E. E., Kubota, Kaoru, Nicholson, Andrew G, Turrisi, Andrew, Beyruti, Ricardo, Eberhardt, Wilfried E.E., Eberhardt, Wilfried EE, Crowley, John   +12 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Role of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Staging of Bladder Cancer [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Dynamic Contrast Enhanced (DCE)-Magnetic Resonance Imaging (MRI) is a useful technique in which rapid enhancement of tumour by uptake of the contrast agent compared to bladder wall.
Elham Rabie, Fariborz Faeghi, Mohammad-Hossein Izadpanahi, Mohammad-Ali Dayani   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Challenges in staging and surveillance of patients with neurofibromatosis and cutaneous malignant melanoma

JPRAS Open, 2019
Summary: Malignant melanoma is a skin neoplasm with a rising trend of incidence. Positron Emission Tomography in combination with Computed Tomography (PET-CT) imaging is an essential diagnostic tool for both staging and surveillance of melanoma patients;
P.R. Chew, V.V. Toh, A. Kotwal
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Restoration Staging, 1660-74

, 2017
Restoration Staging 1660–74 cuts through prevailing ideas of Restoration theatre and drama to read early plays in their original theatrical contexts.
Keenan, Timothy
core   +2 more sources

The value of mediastinoscopy in the staging of lung cancer with clinical N2 disease

Chinese Journal of Lung Cancer, 2008
Background and objective To determine the value of mediastinoscopy in the mediastinal staging of lung cancer with clinical N2 disease. Methods We retrospectively reviewed 87 patients received mediastinoscopy for known or suspected lung cancer, including ...
Hui ZHAO, Jun WANG, Jun LIU, Jianfeng LI, Guanchao JIANG, Yun LI, Fan YANG, Yanguo LIU, Zuli ZHOU   +8 more
doaj  

Enhancing TNM Stage Completeness Using the SEER Summary Stage: A Nationwide Study From Korea [PDF]

Journal of Preventive Medicine and Public Health
Objectives: Accurate and complete cancer staging is essential for effective prognosis and treatment planning. This study investigated the feasibility of enhancing the completeness of tumor‐node‐metastasis (TNM) staging by integrating Surveillance ...
Chang Kyun Choi, Mina Suh, Kyu-Won Jung, E Hwa Yun   +3 more
doaj   +1 more source