Results 41 to 50 of about 2,008,564 (213)

Desmoplastic melanoma: a rare variant with challenging diagnosis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
: Desmoplastic melanoma, a distinct and uncommon variant, is characterized as an invasive lesion with proliferation of fusiform melanocytes in the dermis and subcutaneous tissue, associated with varying patterns of desmoplasia.
Priscila Castelan Marques   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Giant Solitary Fibrous Tumor of the Pleura in Two Cases

open access: yesEurasian Journal of Medicine, 2019
Solitary fibrous tumors of the pleura are rare neoplasms and account for less than 5% of all pleural tumors. They originate from mesenchimal cells of the submesothelial tissue of the pleura. They present as a discrete, pediculated and encapsulated tumor.
Atila Türkyılmaz   +3 more
doaj  

PATHOLOGICAL STUDIES ON LIVER AND BILE DUCT TUMORS IN SUDANESE CATTLE [PDF]

open access: yesAssiut Veterinary Medical Journal
Due to their rare occurrence in bovine species, neoplasms of the liver and bile ducts were reported in few available researches. In Egypt, their prevalence in domestic animals was documented in a few records. An abattoir-based survey was conducted at Abu-
MOHAMED YOUSSEF   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Myxofibrosarcoma: a diagnostic pitfall

open access: yesRare Tumors, 2013
Myxofibrosarcoma (MFS) is a variant of the group of malignant fibrous histiocytomas. It is one of the most aggressive types of soft tissue neoplasms.
Charlotte Castronovo   +3 more
doaj   +1 more source

Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report

open access: yesDermatopathology, 2022
Lobular capillary hemangioma (LCH-PG) is a type of pyogenic granuloma characterized by proliferating blood vessels that resemble conventional granulation tissue. Granulation tissue is very often seen in association with ingrown toenails.
Antonio Córdoba-Fernández   +2 more
doaj   +1 more source

Soft tissue neoplasms: a clinicopathological study [PDF]

open access: yes, 2020
Background: The current WHO classification has categorized soft tissue tumours into benign, malignant and so-called intermediate neoplasms. Soft tissue sarcoma comprises <1% of adult cancers.
K. T., Athulya Krishna Kumar   +3 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy