Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
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Fibrous Dysplasia Meets Intramuscular Myxoma: Mazabraud Syndrome-First Documented Case in Pakistan. [PDF]
Faisal A +6 more
europepmc +1 more source
Generative adversarial networks-based Image-to-Image translation allows tumor consistency prediction from standard MR images in pituitary adenomas. [PDF]
Wu G +13 more
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Solitary Fibrous Tumor of the Greater Omentum with Intratumoral Infarction: A Case Report. [PDF]
Funo T +7 more
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Intraosseous Solitary Fibrous Tumor of the Maxilla: A Report of an Unusual Case. [PDF]
Corredor Y +4 more
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Cervical tracheal resection, laryngectomy, total thyroidectomy and reconstructive stomaplasty for parastomal recurrence of a primary laryngeal malignant fibrous histiocytoma: a case report. [PDF]
Alexieva MS, Rangachev JD, Yankov GS.
europepmc +1 more source
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