Results 221 to 230 of about 1,951,959 (261)

Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues

Advanced Science, EarlyView.
Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali, Mangirdas Malinauskas, Giuseppe Chirico   +2 more
wiley   +1 more source

Nuclear Translocation of PFKFB3 Promotes Disuse‐Induced Muscle Atrophy via Scaffolding Nedd4‐Mediated JunB Ubiquitination

Advanced Science, EarlyView.
Disuse‐induced muscle atrophy is driven by a non‐metabolic, nuclear function of the enzyme PFKFB3. Acting as a scaffold, PFKFB3 facilitates Nedd4‐mediated ubiquitination and degradation of the anti‐atrophy transcription factor JunB. Inhibiting this novel PFKFB3–Nedd4–JunB signaling axis stabilizes JunB and alleviates muscle wasting, revealing a highly ...
Mengjun Ma, Yinliang Liu, Wangchang Wu, Biao Yang, Jiahao Zhuang, Haoye Yu, Rujia Mi, Yixuan Lu, Wen Yang, Hanting Yi, Chenglong Yuan, Yinfeng Gu, Hongyu Li   +12 more
wiley   +1 more source

A Case of Solitary Fibrous Tumor with Tumor Rupture during the Waiting Period for Elective Surgery. [PDF]

Surg Case Rep
Kiriyama A, Poudel S, Takano H, Wada H, Nitta T, Murakami S, Shichinohe T, Takahashi T, Hatanaka KC, Hirano S.   +9 more
europepmc   +1 more source

Giant Fibrous Dysplasia of the Sixth Rib Managed in a Rural, Resource-Limited Setting: A Case Report. [PDF]

Case Rep Orthop
Bhole S, Wilkinson TRV, Nair S, Tiwari A.   +3 more
europepmc   +1 more source

DeepLNM: A Multimodal Model for Predicting Lymph Node Metastasis in Colorectal Cancer

Advanced Science, EarlyView.
Traditional diagnosis may miss positive LNM cases, and pathologists face a workload; therefore, we develop DeepLNM, a multimodal model that predicts lymph node metastasis in colorectal cancer from H&E WSIs, CT images, and text. DeepLNM is robust across internal, external, and prospective cohorts and, in a user study, improves diagnostic accuracy while ...
Zhengyu Zhang, Chengyu Lu, Zhen Wang, Zhijian Cen, Yangshu Zhou, Danyi Li, Qi Xie, Bingbing Li, Shujing Guo, Zhijun Gan, Er‐ran Zhu, Jinbang Li, Aihetaimu Aimaier, Rui Mao, Weihao Qiu, Chenglong Zhao, Ying Tan, Xiaolin Liu, Huiting Ma, Tiansu Geng, Peiyue Wu, Huijun Du, Yu Wang, Yueping Liu, Li Liang   +24 more
wiley   +1 more source

Minimally invasive resection of a spheno-orbital tumor: Review of surgical techniques and a case report. [PDF]

Surg Neurol Int
Adashvoyev K, Boboev J, Rakhimov I, Abduganieva I.   +3 more
europepmc   +1 more source

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin, Yongcheng Chen, Yihao Xie, Dongyang Hu, Longhui Gong, Zhihua Chen, Linjie Chen, Minhao Gao, Qizhu Chen, Morgan Jones, Hui Wang, Xiuling You, Kenny Yat Hong Kwan, Shoutao Weng, Taidong Lyu, Xiang Chen, Yuxiao Zhu, Yusheng Wang, Bin Li, Xiangyang Wang, Xiaofeng Jia, Kailiang Zhou, Ouqiang Wu, Aimin Wu   +23 more
wiley   +1 more source

Spontaneous rupture and hemorrhage of a giant simple hepatic cyst in a 94-year-old woman: a case report. [PDF]

Front Surg
Qiu J, Chen C, Li L.
europepmc   +1 more source

A solitary lytic rib lesion mimicking primary Chest Wall malignancy as the initial presentation of multiple myeloma. [PDF]

Oxf Med Case Reports
Tombul İ, Valiyev E, Akbal Ersöz TA, Zengin M.   +3 more
europepmc   +1 more source

INHAND: Non-proliferative and proliferative lesions of fish - Chapter 13. Fish soft tissues. [PDF]

J Toxicol Pathol
Baumgartner W, Bach U, Baily J, Ruehl-Fehlert C, Fossey S, Furukawa S, Kato Y, Laast V, Meseck E, Schmidt-Posthaus H, Segner H, Shanmukhappa SK, Spitsbergen J, Wolf J.   +13 more
europepmc   +1 more source