Results 91 to 100 of about 46,655 (248)

Gingival and submandibular lymph node metastasis of sigmoid colon adenocarcinoma [PDF]

, 2010
Introduction: Metastatic tumors of oral and maxillofacial region compromise 1% of all malignant oral neoplasms. Most commonly affect the jaw bone and less commonly intraoral soft tissues. They originate mainly from primary tumors of lung, breast, colon-
Boutayeb, L., Elguezabal, A., Gené Hijós, M., Landeyro, Julieta, Martinez, M.S., Mommsen, J., Raventos Estelle, A.   +6 more
core   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Pigmented Bowen’s disease presenting clinically as longitudinal melanonychia

Revista da Sociedade Portuguesa de Dermatologia e Venereologia
Bowen’s disease (BD) is a squamous cell carcinoma, which affects more the elderly population and is more prevalent in light-skinned individuals. It affects most frequently sun-exposed areas and generally manifests as a single erythematous, scaly, or ...
Lucas S. Madureira, Vivian W. Lederman, Julia C. K. El Dib, Paula F. M. Madureira, Lucas K. Fernandes, Eduardo C.N. Constantino   +5 more
doaj  

An integrative modular approach to systematically predict gene-phenotype associations [PDF]

, 2010
Background Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype.
Chao Dai, Juan Nunez-Iglesias, Michael R Mehan, Michael S Waterman, Xianghong Zhou   +4 more
core   +2 more sources

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

Advanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding, Wei Yang, Wenzhao Li, Guifang Xu, Yuanjin Zhao   +4 more
wiley   +1 more source

Characteristics of Anal Fistula Cancer in Patients Who Underwent Surgery: A Nationwide Observational Study Using Diagnosis Procedure Combination Data

Annals of Gastroenterological Surgery, EarlyView.
The characteristics of patients with anal fistula cancer included a higher proportion of men, younger age, more smokers, and tumor‐related characteristics, including more advanced local progression. Surgical characteristics included a lower rate of minimally invasive surgery, a higher proportion of total pelvic exenterations, and longer postoperative ...
Nobuaki Hoshino, Hiromitsu Kinoshita, Kazutaka Obama, Kiyohide Fushimi, Susumu Kunisawa, Yuichi Imanaka   +5 more
wiley   +1 more source

Sinonasal inverted papilloma; recurrence, malignant transformation and risk factors [PDF]

, 2019
Sinonasal inverted papilloma is a rare benign epithelial tumor. Its three main clinical characteristics are the tendency of recurrence, the destructive ability of nearby structures and malignant transformation.
Ghindea, Teodora, Hainarosie, Razvan, Ionita, Irina, Mazilu, Laura, Meius, Alexandru, Nitipir, Cornelia, Pietrosanu, Catalina, Pituru, Silviu, Rusescu, Andreea, Timofte, Daniel   +9 more
core   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Oncocytic carcinoma of parotid gland: a case report with clinical, immunohistochemical and ultrastructural features [PDF]

, 2006
Background Oncocytic carcinoma is an extremely rare neoplasm of the salivary glands. We report a case of oncocytic carcinoma arising in a parotid gland in a 66-year-old female. Method An excisional biopsy of the parotid tumor was performed.
Giovanna Giordano, Marzio Gabrielli, Letizia Gnetti, Teore Ferri, E Guclu, GL Ellis, M Shintaku, T Muramatsu, K Mazutari, GL Ellis, TL Johnson, K Takubo, WL Murphy, J Alberty, M Ghazizadeh, M Takashi, RK Goode   +16 more
core   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source