Results 121 to 130 of about 26,924 (226)
ABSTRACT Background Head and neck cancers (HNCs) are too often diagnosed at advanced stages when outcomes are poor. Additionally, robust tools for the early detection of recurrence remain elusive. These gaps drive interest in so‐called liquid biopsy approaches for HNC detection, prognostication, and surveillance.
Patricia J. Brooks, Scott V. Bratman
wiley +1 more source
What is new in Genitourinary Pathology? Recent developments and highlights of the new 2016 World Health Organization classification of tumors of the urinary system and male genital organs [PDF]
Daniel Abensur Athanazio, Kiril Trpkov
core +1 more source
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano+6 more
wiley +1 more source
Mechanisms of enhancer‐driven oncogene activation
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend+2 more
wiley +1 more source
What's New? Lynch syndrome is a prevalent cause of hereditary gynecological cancers, but the timeline of molecular alterations preceding malignancy remains unclear. By studying consecutive surveillance specimens for up to 15 years before cancer diagnosis, the authors found that atypical endometrial hyperplasia was indistinguishable from endometrial and
Anni K. Kauppinen+3 more
wiley +1 more source
A Rare Cutaneous Tumor With Unusual Dermoscopic Features. [PDF]
Di Guardo A+5 more
europepmc +1 more source
Cancer of the vagina: 2025 update
Abstract Primary vaginal cancer is a rare gynecologic malignancy, with most vaginal cancers representing metastases from other primary sites. Staging and treatment protocols are often extrapolated from those used in cervical cancer. In contemporary medicine, the roles of the pathologist and radiologist are increasingly vital in supporting diagnosis and
Tracey S. Adams+2 more
wiley +1 more source
Glandular cyst mimicking a residual cyst: Case report. [PDF]
Gamri H+3 more
europepmc +1 more source
Cancer of the vulva: 2025 update
Abstract Vulvar cancer is an uncommon gynecological malignancy primarily affecting postmenopausal women. No specific screening exists and the most effective strategy to reduce the incidence of vulvar cancer is the opportune treatment of predisposing and preneoplastic lesions associated with its development.
Alexander B. Olawaiye+3 more
wiley +1 more source
Treatment Outcomes of Sinonasal Seromucinous Hamartoma: A Single-Center Experience. [PDF]
Lee DH, Lim SC.
europepmc +1 more source