Results 131 to 140 of about 44,661 (225)

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano   +6 more
wiley   +1 more source

Mechanisms of enhancer‐driven oncogene activation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend   +2 more
wiley   +1 more source

Dienogest use and the risk of breast and gynecologic cancers: A nationwide population‐based study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate whether dienogest exposure is associated with the risk of breast, endometrial, or tubo‐ovarian cancer in women with endometriosis. Methods In this nationwide retrospective cohort study (January 2012 to December 2023), we used the Korean National Health Insurance Review & Assessment Service database. Women aged 20–49 years
Hoyol Jhang   +4 more
wiley   +1 more source

Liposarcoma Arising From Mature Teratoma Following Testicular Tumor Surgery: A Case Report

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Testicular germ cell tumors (GCTs) are rare cancers. Mature teratomas may rarely undergo somatic malignant transformation (SMT) and may exhibit histological features resembling those of sarcomas. Case A 22‐year‐old male presented to our hospital with a complaint of a left scrotal mass.
Mai Yamazaki   +8 more
wiley   +1 more source

Exploring the Capability of Spectral Detector Computed Tomography to Identify Zinc and Magnesium in the Prostate Gland: A Proof‐of‐Concept Study

open access: yesiRADIOLOGY, EarlyView.
ABSTRACT Background Prostate cancer is one of the most common diagnosed cancers globally, with early detection crucial for reducing mortality and morbidity. However existing screening methods have limitations, such as invasiveness and patient discomfort.
Jacqueline Scheicher   +4 more
wiley   +1 more source

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