Results 61 to 70 of about 42,041 (231)

Combined goblet cell carcinoid and mucinous cystadenoma of the vermiform appendix.

, 2009
Goblet cell carcinoid is an uncommon primary tumor of the vermiform appendix, characterized by dual endocrine and glandular differentiation. Whether goblet cell carcinoid represents a morphological variant of appendiceal classical carcinoid or a mucin ...
Chetty, R, Serra, S, Chetty, Runjan, Alsaad, KO, Runjan Chetty, Stefano Serra, Khaled O Alsaad   +6 more
core   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Adenocarcinoma of the Uterine Cervix Detected Over Long-Term Mass Screening in Japan [PDF]

We retrospectively reviewed the history, records of detailed examination and/or treatment, and cytologic/histologic specimens of 32 adenocarcinoma cases (0.006%) detected among 482,451 examinees in a mass screening for cervical cancer conducted over a 20-
Moriyama, Shingo, Ishimaru, Tadayuki, Takao, Naohiro, Nakajima, Hisayoshi, Hayashida, Mitsunori, Sakai, Hidetaka, Fujishita, Akira   +6 more
core   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Redefining the Role of Splenectomy in Scirrhous Gastric Cancer: Toward a Selective Multimodal Strategy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Scirrhous gastric cancer, characterized by diffuse infiltration and a high propensity for peritoneal dissemination, remains one of the most aggressive subtypes of gastric cancer. Despite a relatively high incidence of splenic hilar lymph node (No. 10) metastasis, the oncologic benefit of splenectomy remains controversial, while its association
Tsutomu Hayashi, Takaki Yoshikawa
wiley   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Transcriptional evidence of neuroendocrine cell plasticity beyond histological boundaries in lung neuroendocrine neoplasms: an in-silico analysis suggesting a progression model

Journal of Experimental & Clinical Cancer Research
Little is known as to whether there may be a patogenetic continuum among subsets of lung neuroendocrine neoplasms (NENs), including both neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs).
Giuseppe Pelosi, Mauro Papotti, Riccardo Papa, Eleonora Duregon, Maria Gemelli, Sergio Harari, Angelica Sonzogni, Alice Laffi, Tommaso De Pas, Chiara Catania, Barbara Bassani, Fiorenza Lotti, Antonino Bruno, Paola Muti, Fabrizio Bianchi   +14 more
doaj   +1 more source

Bronchoscopy Robot with Enhanced Flexibility and Stability via Multi‐Segment Variable Stiffness Catheter

Advanced Intelligent Systems, EarlyView.
This work presents a magnetic bronchoscopy robot with a novel multi‐segment variable stiffness catheter. This catheter can not only move flexibly in the narrow bronchi but also harden according to the need to provide support. Combined with remote wireless magnetic field drive, it provides a more precise and effective solution for biopsy of deep lung ...
Shucong Yin, Bin Huang, Shiyuan Dong, Junhao Wang, Liangshen Zhao, Yang Yang, Bingkun Bao, Hongen Liao, Fang Chen, Tianqi Huang, Boyu Zhang   +10 more
wiley   +1 more source

Analysis of Clinicopathological Features of Cervical Mucinous Adenocarcinoma with a Solitary Ovarian Metastatic Mass as the First Manifestation

Cancer Management and Research, 2020
Shuanghuan Liu,1 Yunquan Guo,2,3 Bin Li,1 Huijuan Zhang,2 Rong Zhang,1 Shan Zheng2 1Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking ...
Liu S, Guo Y, Li B, Zhang H, Zhang R, Zheng S   +5 more
doaj