Results 91 to 100 of about 991,497 (309)

P53 mutations in human adrenocortical neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B., Chrousos, G. P., Karl, M., Linehan, M., Mastorakis, G., Reincke, Martin, Travis, W.   +6 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Clinicopathologic Characteristics of Patients with Gastric Superficial Neoplasia and Risk Factors for Multiple Lesions after Endoscopic Submucosal Dissection in a Western Country

GE: Portuguese Journal of Gastroenterology, 2019
Background: Endoscopic submucosal dissection (ESD) is a treatment for early gastric neoplasms that preserves the stomach. However, the risk of multiple lesions persists.
Gisela Brito-Gonçalves, Diogo Libânio, Pedro Marcos, Inês Pita, Rui Castro, Inês Sá, Mário Dinis-Ribeiro, Pedro Pimentel-Nunes   +7 more
doaj   +1 more source

Serous cystic neoplasm of the pancreas: A multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas) [PDF]

, 2015
OBJECTIVES: Serous cystic neoplasm (SCN) is a cystic neoplasm of the pancreas whose natural history is poorly known. The purpose of the study was to attempt to describe the natural history of SCN, including the specific mortality.
Aguero Garcete, G., Angiolini, M. R., Araujo Acuna, I., Arcidiacono, P. G., Balzano, G., Bassi, C., Bernier, B., Bissolati, M., Bolado, F., Brugge, W., Campos, V., Casadei, R., Choi, H. J., Concepcion Martin, M., Conwell, D., Crippa, S., De Angelis, C. G., Del Chiaro, M., Delhaye, M., Faccinetto, A., Falconi, M., Fern\ue1ndez Del Castillo, C., Fontana, M., Frigerio, I., Frulloni, L., Gill, R. S., Girelli, R., Gomatos, I., Ha, Y., Hirai, I., Hruban, R., Huggett, M. T., Ikeura, T., Jais, B., Jang, J. Y., Jang, K. T., Jung, W., Kang, C. M., Kang, H., Keane, M. G., Kim, M. H., Kim, S. W., Kimura, W., Kopchak, K. V., L\ue9vy, P., Lee, L. S., Lee, W. J., Lennon, A. M., Leong, R. W., Maggino, L., Malleo, G., Manfredi, R., Marchegiani, G., Matsumoto, I., Messina, O., Milanetto, Anna Caterina, Moon, J. H., Moran, R., Morana, G., Napoleon, B., Neoptolemos, J., Oh, D., Okazaki, K., Oppong, K. W., Osvaldt, A., Oua\uefssi, M., Pavey, D., Pereira, S. P., Pererva, L., Petrone, M. C., Rebours, V., Ricci, C., Rios Vives, M. A., Salvia, R., Sastre, B., Segersvard, R., Shinzeki, M., Song, D. H., Song, S. Y., Spandre, M., Sperti, Cosimo, Tang, J., Urman Fernandez, J. M., Vaquero, E. C., Wang, H., Wolfgang, C., Zaheer, A., Zerbi, A.   +87 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Synchronous Bilateral Warthin Tumors: A Case Report

International Archives of Otorhinolaryngology, 2014
Introduction Warthin tumor is described as papillary cystadenoma lymphomatosum and is the second most common tumor of the parotid glands. Bilateral synchronous incidence is rare, occurring in 7 to 10% of the cases.
Luiz Augusto Nascimento, Julia Alessandra Santos Ferreira, Raquel Baptista Pio, Gustavo Henrique Soares Takano, Hélcio Luiz Miziara   +4 more
doaj   +1 more source

Maxillary osteosarcoma in a beef suckler cow [PDF]

, 2012
A ten-year-old beef suckler cow was referred to the Scottish Centre for Production Animal Health and Food Safety of the University of Glasgow, because of facial swelling in the region of the right maxilla.
Barrett, D.C., Prins, D.G.J., Wittek, T.
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Role of Fine Needle Aspiration Cytology in Salivary Gland Pathology and its Histopathological Correlation: A Two Year Prospective Study in Western India. [PDF]

, 2012
Background and objectives: Salivary gland lesions account for 2-6.5% of all the neoplasms of the head and neck. Fine needle aspiration cytology (FNAC) is being increasingly used in the diagnosis of salivary gland lesions.
Agravat, AH, Dhruva, GA, Pujara, KM, Sanghvi, HK   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source