Mutational Analysis of Ionizing Radiation Induced Neoplasms [PDF]
Cell Reports, 2015 Ionizing radiation (IR) is a mutagen that promotes tumorigenesis in multiple exposure contexts. One severe consequence of IR is the development of second malignant neoplasms (SMNs), a radiotherapy-associated complication in survivors of cancers ...
Amy L. Sherborne +5 more
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Risk of radiation-induced second malignant neoplasms from photon and proton radiotherapy in paediatric abdominal neuroblastoma [PDF]
Physics and Imaging in Radiation Oncology, 2021 Background and Purpose: State-of-the-art radiotherapy modalities have the potential of reducing late effects of treatment in childhood cancer survivors. Our aim was to investigate the carcinogenic risk associated with 3D conformal (photon) radiation (3D ...
Sophie Taylor +9 more
doaj +5 more sources
Spontaneous and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms [PDF]
Frontiers in Oncology, 2020 The purpose of the present study was to investigate whether former childhood cancer patients who developed a subsequent secondary primary neoplasm (SPN) are characterized by elevated spontaneous chromosomal instability or cellular and chromosomal ...
Sebastian Zahnreich +12 more
doaj +7 more sources
Сибирский онкологический журнал, 2019 The goal of radiotherapy is to maximize the radiation dose to abnormal cancer cells while preventing damage to healthy tissue. in neutron therapy, the optimum regime of treatment is uncertain to date.The purpose of the study to develop a set of ...
E. L. Choynzonov +4 more
doaj +4 more sources
American Journal of Case Reports, 2020 BACKGROUND Following craniospinal irradiation in children with medulloblastoma, secondary neoplasms are among the most serious long-term sequelae that include leukemias and solid tumors of the urinary or digestive tracts, thyroid, skin, and central nervous system.
Yasser Orz +6 more
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Radiation-induced neoplasms following curative therapy for retinoblastoma [PDF]
Cancer, 1966 Twenty‐two cases of radiation induced neoplasms following curative therapy for retinoblastoma are reviewed, and three new cases are reported. Twenty‐four of the 25 growths were malignant, and most were of the osteogenic series and its variants. The young
H. Soloway
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Stereotactic Radiation for Treating Primary and Metastatic Neoplasms of the Spinal Cord
Frontiers in Oncology, 2020 Stereotactic radiation treatment can be used to treat spinal cord neoplasms in patients with either unresectable lesions or residual disease after surgical resection.
Elisa K. Liu +4 more
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Time Dependence of Radiation-induced Hypothalamic–Pituitary Axis Dysfunction in Adults Treated for Non-pituitary, Intracranial Neoplasms [PDF]
Clinical Oncology, 2017 AIMS: Hypothalamic-pituitary axis (HPA) dysfunction is a sequela of cranial radiotherapy. The purpose of this study was to use endocrine data from existing publications to characterise the baseline endocrine status, the effects of radiotherapy on the HPA during the first follow-up year and the time dependence of radiation-induced HPA dysfunction in ...
N. Taku +4 more
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Susceptibility Loci and Chromosomal Abnormalities in Radiation Induced Hematopoietic Neoplasms in Mice [PDF]
Journal of Radiation Research, 2011 Genetics of susceptibility to radiation-induced hematopoietic neoplasms and somatic chromosomal aberrations were analyzed in 305 backcross (CcS-17xCcS-2)xCcS-2 mice of two CcS/Dem recombinant congenic strains. Irradiated CcS-2 mice were previously shown to exhibit high frequency of myeloid neoplasms whereas irradiated CcS-17 mice were susceptible to T ...
Alina Czarnomska +9 more
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Unusual Presentation of Bilateral Radiation-Induced Angiosarcoma of the Breast
Case Reports in Oncological Medicine, 2020 Radiation-induced sarcoma of the breast is an iatrogenic malignancy that occurs secondary to radiotherapy, which is most commonly given following breast conservation surgery.
Umesh Jayarajah +3 more
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