Time Dependence of Radiation-induced Hypothalamic-Pituitary Axis Dysfunction in Adults Treated for Non-pituitary, Intracranial Neoplasms. [PDF]
Clinical Oncology, 2017 AIMS: Hypothalamic-pituitary axis (HPA) dysfunction is a sequela of cranial radiotherapy. The purpose of this study was to use endocrine data from existing publications to characterise the baseline endocrine status, the effects of radiotherapy on the HPA during the first follow-up year and the time dependence of radiation-induced HPA dysfunction in ...
N. Taku +4 more
semanticscholar +4 more sources
Cells, 2021 Gynaecologic cancers are common among women and treatment includes surgery, radiotherapy or chemotherapy, where the last two methods induce DNA damage in non-targeted cells like peripheral blood lymphocytes (PBL).
Aneta Węgierek-Ciuk +6 more
doaj +2 more sources
Radiation‐induced intracranial neoplasms. A report of three possible cases [PDF]
Cancer, 1984 The pathologic findings are described in three patients who developed second intracranial neoplasms after irradiation for central nervous system malignancy. The second neoplasms were an astrocytoma, an ependymoma, and multiple meningiomas. All were histologically different from the first neoplasms and appeared in the field of irradiation between 3 and ...
Janice R. Anderson, C. Treip
semanticscholar +3 more sources
Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1). [PDF]
PLoS ONE, 2017 An understanding of how each individual 5q chromosome critical deleted region (CDR) gene contributes to malignant transformation would foster the development of much needed targeted therapies for the treatment of therapy related myeloid neoplasms (t-MNs).
Karine Z Oben +7 more
doaj +2 more sources
Intramedullary Glioblastoma as One of Multiple Radiation-Induced Neoplasms
Case Reports in OncologyIntroduction: Intramedullary glioblastoma is a rare entity comprising 1.4–9% of spinal gliomas. Spinal cord radiation-induced gliomas are unique, with only 13 cases reported to date.
K. Koczyk +6 more
semanticscholar +2 more sources
Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms. [PDF]
Cancer Research, 2012 Abstract Second malignant neoplasms (SMN) are therapy-induced malignancies and a growing problem in cancer survivors, particularly survivors of childhood cancers. The lack of experimental models of SMNs has limited understanding of their pathogenesis.
Grace Choi +8 more
semanticscholar +6 more sources
Susceptibility loci and chromosomal abnormalities in radiation induced hematopoietic neoplasms in mice. [PDF]
Journal of Radiation Research, 2011 Genetics of susceptibility to radiation-induced hematopoietic neoplasms and somatic chromosomal aberrations were analyzed in 305 backcross (CcS-17xCcS-2)xCcS-2 mice of two CcS/Dem recombinant congenic strains.
J. Piskorowska +9 more
semanticscholar +3 more sources
Radiation-Induced Brain Injury: Mechanistic Insights and the Promise of Gut–Brain Axis Therapies
Brain SciencesRadiation therapy is widely recognized as an efficacious modality for treating neoplasms located within the craniofacial region. Nevertheless, this approach is not devoid of risks, predominantly concerning potential harm to the neural structures. Adverse
Mengting Li +3 more
doaj +2 more sources
Radiation‐induced neoplasms following curative therapy for retinoblastoma [PDF]
Cancer, 1966 H. Soloway
semanticscholar +3 more sources
Proton Radiotherapy to Reduce Late Complications in Childhood Head and Neck Cancers [PDF]
International Journal of Particle Therapy, 2021 In most childhood head and neck cancers, radiotherapy is an essential component of treatment; however, it can be associated with problematic long-term complications.
Michael T. Spiotto, MD, PhD +6 more
doaj +1 more source