Results 221 to 230 of about 4,887,141 (260)

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

Post-therapy imaging of adult brain tumours: patterns, pitfalls, and practical framework. [PDF]

Insights Imaging
Isaac MFG.
europepmc   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

Advanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li   +7 more
wiley   +1 more source

Sublethal Caspase-8 Activation Drives Radiation-Induced Genetic Instability and Oncogenic Transformation Through Endonuclease G and Non-Canonical NF-κB Signaling. [PDF]

Int J Mol Sci
Zhu C, Li X, Li CY, Liu R, Wang Y.
europepmc   +1 more source

Supramolecular Chiral Assemblies from Benzoselenadiazole‐Alanine‐Acylhydrazone Conjugates Enable Cardioprotection

Advanced Science, EarlyView.
The C3‐symmetric conjugate TASe, which integrates benzoselenadiazole, alanine, and acylhydrazone modules, self‐assembles into a chalcogen‐/hydrogen‐bonded porous framework in the solid state and uniform chiral nanospheres in aqueous media. These assemblies protect cardiomyocytes from doxorubicin‐induced oxidative injury by scavenging intracellular ...
Jinkui Teng, Renjing Yang, Yu Du, Jingzhong Duan, Yiming Xu, Zhihua He, Guanghui Wang, Wenjing Tian, Aijie Liu, Haifeng Chen, Yun‐Bao Jiang, Xiaosheng Yan   +11 more
wiley   +1 more source

Proton arc therapy reduces the dose delivered to circulating blood compared to intensity-modulated proton therapy for head-and-neck cancer. [PDF]

J Appl Clin Med Phys
Tattenberg S, Liu P, Cong X, Hoehr C, Ding X.   +4 more
europepmc   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

Radiation-Induced Morphea of the Breast in a Patient with Pre-Existing Mycosis Fungoides: A Diagnostic Challenge. [PDF]

Curr Oncol
Mobayed T, Eid T, Abbas O, Moukadem H, El Saghir N, Ayoub Z.   +5 more
europepmc   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

Radiotherapy-induced oxidative stress and mitochondrial dysfunction: potential contributions of toxic elements and associated biomarkers-a systematic review. [PDF]

Front Public Health
Alharkan AAS, Emara AM, Barghash SS.
europepmc   +1 more source